This review focuses on the smart chemistry that has been utilized in developing polymer-
based drug delivery systems over the past 10 years. We provide a comprehensive overview …

Incorporating labile bonds inside polymer backbone and side chains yields interesting
polymer materials that are responsive to change of environmental stimuli. Drugs can be …

Polymeric nanostructured materials (PNMs), which are polymeric materials in nanoscale or
polymer composites containing nanomaterials, have become increasingly useful for …

A key end goal of gene delivery research is to develop clinically relevant vectors that can be
used to combat elusive diseases such as AIDS. Despite promising engineering strategies …

Metal–organic frameworks (MOFs), which are typically embedded in polymer matrices as
composites, are emerging as a new class of carriers for sustained drug delivery. Most of the …

Control over bottlebrush polymer synthesis by ring-opening metathesis polymerization
(ROMP) of macromonomers (MMs) is highly dependent on the competition between the …

Highly branched “bottlebrush” polymers are a class of macromolecules characterized by
side chains that are densely grafted from a backbone that is typically linear. Their unique …

The development of controlled/living polymerization methodologies has underpinned a
rapid expanse in our understanding of amphiphilic block copolymer self-assembly. In …

Paclitaxel (PTX) is one of the most successful drugs ever used in cancer chemotherapy,
acting against a variety of cancer types. Formulating PTX with Cremophor EL and ethanol …

Nanomaterials have great potential to offer effective treatment against devastating diseases
by providing sustained release of high concentrations of therapeutic agents locally …