This review focuses on mechanisms and emerging concepts that drive the science of stroke
in a therapeutic direction. Once considered exclusively a disorder of blood vessels, growing …

Conventional angiographic evaluation has advantages, including its reliable demonstration
of occlusion versus subtotal occlusion, well standardized recanalization grading, and high …

The brain vasculature has been increasingly recognized as a key player that directs brain
development, regulates homeostasis, and contributes to pathological processes. Following …

Restorative cell-based and pharmacological therapies for experimental stroke substantially
improve functional outcome. These therapies target several types of parenchymal cells …

Angiogenesis serves as an important protective mechanism against ischemic stroke,
because angiogenesis promotes the generation of collateral circulation and consequently …

Abstract Introduction Neural stem cells (NSCs) have demonstrated multimodal therapeutic
function for stroke, which is the leading cause of long‐term disability and the second leading …

Pathophysiological processes of stroke have revealed that the damaged brain should be
considered as an integral structure to be protected. However, promising neuroprotective …

Angiogenesis is a key process in organ and tissue morphogenesis, as well as growth during
human development, and is coordinated by pro-and anti-angiogenic factors. When this …

The biological processes underlying stroke are complex, and patients have a narrow
repertoire of therapeutic opportunities. After the National Institutes of Health (NIH) convened …

Interaction between angiogenesis and axonal remodeling after stroke was dynamically
investigated by MRI in rats with or without sildenafil treatments. Male Wistar rats were …