Varicocele and male infertility: part II: pathophysiology of varicoceles in male infertility

CK Naughton, AK Nangia… - Human reproduction …, 2001 - academic.oup.com
Varicoceles are found in 19 to 41% of infertile men, and is one treatable form of male
infertility. The mechanism by which varicoceles cause the variable effect on male infertility …

Effect of varicocele repair on sperm DNA fragmentation: a review

M Roque, SC Esteves - International urology and nephrology, 2018 - Springer
Varicocele, the leading cause of male infertility, can impair sperm quality and fertility via
various oxidative stress mechanisms. An imbalance between excessive reactive oxygen …

Elevated scrotal temperature, but not varicocele grade, reflects testicular oxidative stress-mediated apoptosis

K Shiraishi, H Takihara, H Matsuyama - World journal of urology, 2010 - Springer
Purpose Elevation of scrotal temperature has been known as a cause of male infertility but
the exact mechanism leading to impaired spermatogenesis is unknown. This work aimed to …

Pathophysiology of varicocele in male infertility in the era of assisted reproductive technology

K Shiraishi, H Matsuyama… - International journal of …, 2012 - Wiley Online Library
Varicocele is the most common and treatable cause of male infertility. Studies of a rat
experimental left varicocele model and human testicular biopsy samples have shown the …

Role of oxidative stress in pathogenesis of varicocele and infertility

A Agarwal, RK Sharma, NR Desai, S Prabakaran… - Urology, 2009 - Elsevier
This review summarizes the published literature about the role of oxidative stress in the
pathophysiology of varicocele and the beneficial effects of varicocele repair on oxidative …

Insight into oxidative stress in varicocele-associated male infertility: part 2

A Hamada, SC Esteves, A Agarwal - Nature Reviews Urology, 2013 - nature.com
Varicocele, the leading cause of male infertility, can impair spermatogenesis through several
pathophysiological mechanisms. Of these, current evidence suggests that oxidative stress is …

[HTML][HTML] Increased seminal reactive oxygen species levels in patients with varicoceles correlate with varicocele grade but not with testis size

SSR Allamaneni, CK Naughton, RK Sharma… - Fertility and sterility, 2004 - Elsevier
Increased levels of reactive oxygen species (ROS) are associated with clinical varicoceles;
however, its correlation with varicocele grade and testis size is unknown. In our study …

Effect of varicoceles on spermatogenesis

C Kang, N Punjani, RK Lee, PS Li… - Seminars in Cell & …, 2022 - Elsevier
Varicoceles are dilated veins within the spermatic cord and a relatively common occurrence
in men. Fortunately, the large majority of men are asymptomatic, however, a proportion of …

Effect of varicocele on sperm function and semen oxidative stress

CG Blumer, AE Restelli, PTD Giudice… - BJU …, 2012 - Wiley Online Library
Study Type–Aetiology (case control) Level of Evidence 3b What's known on the subject?
and What does the study add? Varicocele leads to alterations in sperm DNA integrity even …

Seminal reactive oxygen species‐antioxidant relationship in fertile males with and without varicocele

T Mostafa, T Anis, H Imam, AR El‐Nashar… - Andrologia, 2009 - Wiley Online Library
The aim of this study was to assess seminal reactive oxygen species (ROS)‐antioxidants
relationship in fertile and infertile men with and without varicocele. One hundred and …