Evolution and advancements in genomics and epigenomics in OA research: How far we have come

YFM Ramos, SJ Rice, SA Ali, C Pastrello… - Osteoarthritis and …, 2024 - Elsevier
Objective Osteoarthritis (OA) is the most prevalent musculoskeletal disease affecting
articulating joint tissues, resulting in local and systemic changes that contribute to increased …

Opportunities and challenges in microRNA research and clinical application

CM Klinge - Endocrinology, 2023 - academic.oup.com
However, they caution the reader about the impact of anticoagulants in the collection tube
that inhibit the reverse transcription (RT) step prior to quantitative polymerase chain reaction …

[PDF][PDF] Extracellular MicroRNAs as Potential Biomarkers for Frail Kidney Phenotype: Progresses and Precautions

CT Chao, CK Chiang, KY Hung - Aging and disease, 2023 - scholar.archive.org
Frailty describes the cumulative subtle health deficits leading to an increased vulnerability to
insults among older individuals or disease-laden ones. The prevalence of frailty increases …

Molecular mechanism of miRNA mediated biosynthesis of secondary metabolites in medicinal plants

H Li, Z Guo, M Xu, J Zhao, D Xu - Plant Physiology and Biochemistry, 2024 - Elsevier
Plant secondary metabolites are important raw materials for the pharmaceutical industry,
and their biosynthetic processes are subject to diverse and precise regulation by miRNA …

RNA-Binding Protein Motifs Predict microRNA Secretion and Cellular Retention in Hypothalamic and Other Cell Types

W He, DD Belsham - Biomedicines, 2024 - mdpi.com
Cellular microRNAs (miRNAs) can be selectively secreted or retained, adding another layer
to their critical role in regulating human health and disease. To date, select RNA-binding …

Quantitative analysis of piwiRNAs in the culture medium of euploid and aneuploid blastocysts as an additional method of selecting a high-quality embryo for transfer to …

AV Timofeeva, IS Fedorov… - Obstetrics and …, 2023 - journals.eco-vector.com
Objective: To identify piwiRNAs in the culture medium of a blastocyst associated with cell
ploidy and the implanting ability of an embryo after transfer into the uterine cavity. Materials …