New psychoactive substances: challenges for drug surveillance, control, and public health responses

A Peacock, R Bruno, N Gisev, L Degenhardt, W Hall… - The Lancet, 2019 - thelancet.com
The rapid emergence since the mid-2000s of a large and diverse range of substances
originally designed as legal alternatives to more established illicit drugs (pragmatically …

[HTML][HTML] Designer drugs: mechanism of action and adverse effects

D Luethi, ME Liechti - Archives of toxicology, 2020 - Springer
Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

[HTML][HTML] “Zombie” outbreak caused by the synthetic cannabinoid AMB-FUBINACA in New York

AJ Adams, SD Banister, L Irizarry, J Trecki… - New England journal …, 2017 - Mass Medical Soc
Background New psychoactive substances constitute a growing and dynamic class of
abused drugs in the United States. On July 12, 2016, a synthetic cannabinoid caused mass …

Synthesis and in Vitro Cannabinoid Receptor 1 Activity of Recently Detected Synthetic Cannabinoids 4F-MDMB-BICA, 5F-MPP-PICA, MMB-4en-PICA, CUMYL …

A Cannaert, E Sparkes, E Pike, JL Luo… - ACS Chemical …, 2020 - ACS Publications
Synthetic cannabinoid receptor agonists (SCRAs) are an evolving class of new psychoactive
substances (NPS) with structurally diverse compounds emerging each year. Due to the rapid …

Reports of adverse events associated with use of novel psychoactive substances, 2013–2016: a review

BK Logan, ALA Mohr, M Friscia… - Journal of Analytical …, 2017 - academic.oup.com
Novel psychoactive substances (NPS) represent significant analytical and interpretive
challenges to forensic and clinical toxicologists. Timely access to case reports and reports of …

[HTML][HTML] Synthetic cannabinoids: a pharmacological and toxicological overview

R Roque-Bravo, RS Silva, RF Malheiro… - Annual review of …, 2023 - annualreviews.org
Synthetic cannabinoids (SCs) are a chemically diverse group of new psychoactive
substances (NPSs) that target the endocannabinoid system, triggering a plethora of actions …

[HTML][HTML] Analysis of cannabinoid-containing fluids in illicit vaping cartridges recovered from pulmonary injury patients: identification of vitamin E acetate as a major …

B Duffy, L Li, S Lu, L Durocher, M Dittmar… - Toxics, 2020 - mdpi.com
Beginning in June of 2019, there was a marked increase in reported cases of serious
pulmonary injury associated with vaping. The condition, referred to as e-cigarette or vaping …

Absence of Entourage: Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Functional Activity of Δ9-THC at Human CB1 and CB2 Receptors

M Santiago, S Sachdev, JC Arnold… - Cannabis and …, 2019 - liebertpub.com
Abstract Introduction: Compounds present in Cannabis sativa such as phytocannabinoids
and terpenoids may act in concert to elicit therapeutic effects. Cannabinoids such as Δ9 …

Death cases involving certain new psychoactive substances: a review of the literature

M Kraemer, A Boehmer, B Madea, A Maas - Forensic science international, 2019 - Elsevier
In the last decades, more and more new psychoactive substances (NPS) were introduced on
the drug market which were sold as “legal” alternatives for classic drugs and misused …

Synthetic cannabinoid receptor agonists: classification and nomenclature

AJ Potts, C Cano, SHL Thomas, SL Hill - Clinical Toxicology, 2020 - Taylor & Francis
Introduction: The emergence of novel psychoactive substances has changed the
epidemiology of drugs used recreationally throughout Europe and have posed significant …