[PDF][PDF] Impact of computational approaches in the fight against COVID-19: an AI guided review of 17 000 studies

F Napolitano, X Xu, X Gao - Briefings in bioinformatics, 2022 - academic.oup.com
SARS-CoV-2 caused the first severe pandemic of the digital era. Computational approaches
have been ubiquitously used in an attempt to timely and effectively cope with the resulting …

Peptide-based vaccines in clinical phases and new potential therapeutic targets as a new approach for breast cancer: a review

ML Nicolas-Morales, A Luisa-Sanjuan… - Vaccines, 2022 - mdpi.com
Breast cancer is the leading cause of death in women from 20 to 59 years old. The
conventional treatment includes surgery, chemotherapy, hormonal therapy, and …

Contriving multi-epitope subunit of vaccine for COVID-19: immunoinformatics approaches

R Dong, Z Chu, F Yu, Y Zha - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has recently become the most serious threat to public health, and its prevalence
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …

Designing a Next-Generation Multiepitope-Based Vaccine against Staphylococcus aureus Using Reverse Vaccinology Approaches

SR Mahapatra, J Dey, TK Raj, N Misra, M Suar - Pathogens, 2023 - mdpi.com
Staphylococcus aureus is a human bacterial pathogen that can cause a wide range of
symptoms. As virulent and multi-drug-resistant strains of S. aureus have evolved, invasive S …

Design of a multi-epitope-based vaccine targeting M-protein of SARS-CoV2: an immunoinformatics approach

VS Ayyagari, V TC, AP K, K Srirama - Journal of biomolecular …, 2022 - Taylor & Francis
In the present study, one of the targets present on the envelopes of coronaviruses,
membrane glycoprotein (M) was chosen for the design of a multi-epitope vaccine by …

Bioinformatics analysis and consistency verification of a novel tuberculosis vaccine candidate HP13138PB

P Cheng, F Jiang, G Wang, J Wang, Y Xue… - Frontiers in …, 2023 - frontiersin.org
Background With the increasing incidence of tuberculosis (TB) and the shortcomings of
existing TB vaccines to prevent TB in adults, new TB vaccines need to be developed to …

In silico design and analyses of a multi-epitope vaccine against Crimean-Congo hemorrhagic fever virus through reverse vaccinology and immunoinformatics …

AA Omoniyi, SS Adebisi, SA Musa, JO Nzalak… - Scientific Reports, 2022 - nature.com
Abstract Crimean Congo Hemorrhagic Fever virus (CCHFV) is a deadly human pathogen
that causes an emerging zoonotic disease with a broad geographic spread, especially in …

Development of multi-epitope vaccines against the monkeypox virus based on envelope proteins using immunoinformatics approaches

C Tan, F Zhu, P Pan, A Wu, C Li - Frontiers in Immunology, 2023 - frontiersin.org
Background Since May 2022, cases of monkeypox, a zoonotic disease caused by the
monkeypox virus (MPXV), have been increasingly reported worldwide. There are, however …

Immuno-informatics profiling of monkeypox virus cell surface binding protein for designing a next generation multi-valent peptide-based vaccine

M Yousaf, S Ismail, A Ullah, S Bibi - Frontiers in Immunology, 2022 - frontiersin.org
Monkeypox is a viral etiological agent with hallmarks analogous to those observed in
smallpox cases in the past. The ongoing outbreak of Monkeypox viral infection is becoming …

PP19128R, a Multiepitope Vaccine Designed to Prevent Latent Tuberculosis Infection, Induced Immune Responses In Silico and In Vitro Assays

F Jiang, C Peng, P Cheng, J Wang, J Lian, W Gong - Vaccines, 2023 - mdpi.com
Background: Latent tuberculosis infection (LTBI) is the primary source of active tuberculosis
(ATB), but a preventive vaccine against LTBI is lacking. Methods: In this study, dominant …