Agarose-based biomaterials for tissue engineering
Agarose is a natural polysaccharide polymer having unique characteristics that give reason
to consider it for tissue engineering applications. Special characteristics of agarose such as …
to consider it for tissue engineering applications. Special characteristics of agarose such as …
[HTML][HTML] The extracellular matrix: Tools and insights for the “omics” era
The extracellular matrix (ECM) is a fundamental component of multicellular organisms that
provides mechanical and chemical cues that orchestrate cellular and tissue organization …
provides mechanical and chemical cues that orchestrate cellular and tissue organization …
MatrisomeDB: the ECM-protein knowledge database
The extracellular matrix (ECM) is a complex and dynamic meshwork of cross-linked proteins
that supports cell polarization and functions and tissue organization and homeostasis. Over …
that supports cell polarization and functions and tissue organization and homeostasis. Over …
Ten years of extracellular matrix proteomics: accomplishments, challenges, and future perspectives
A Naba - Molecular & Cellular Proteomics, 2023 - ASBMB
The extracellular matrix (ECM) is a complex assembly of hundreds of proteins forming the
architectural scaffold of multicellular organisms. In addition to its structural role, the ECM …
architectural scaffold of multicellular organisms. In addition to its structural role, the ECM …
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices
The extracellular matrix (ECM) is a complex meshwork of cross-linked proteins providing
both biophysical and biochemical cues that are important regulators of cell proliferation …
both biophysical and biochemical cues that are important regulators of cell proliferation …
The thrombospondins
JC Adams, J Lawler - Cold Spring Harbor perspectives …, 2011 - cshperspectives.cshlp.org
Thrombospondins are evolutionarily conserved, calcium-binding glycoproteins that undergo
transient or longer-term interactions with other extracellular matrix components. They share …
transient or longer-term interactions with other extracellular matrix components. They share …
Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells
V Severino, N Alessio, A Farina, A Sandomenico… - Cell death & …, 2013 - nature.com
Cellular senescence is the permanent arrest of cell cycle, physiologically related to aging
and aging-associated diseases. Senescence is also recognized as a mechanism for limiting …
and aging-associated diseases. Senescence is also recognized as a mechanism for limiting …
Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: a proteomics approach
Abdominal aortic aneurysms (AAA) are characterized by pathological remodeling of the
aortic extracellular matrix (ECM). However, besides the well-characterized elastolysis and …
aortic extracellular matrix (ECM). However, besides the well-characterized elastolysis and …
Defining the extracellular matrix using proteomics
A Byron, JD Humphries… - International journal of …, 2013 - Wiley Online Library
The cell microenvironment has a profound influence on the behaviour, growth and survival
of cells. The extracellular matrix (ECM) provides not only mechanical and structural support …
of cells. The extracellular matrix (ECM) provides not only mechanical and structural support …
Proteomic analysis of naturally-sourced biological scaffolds
A key challenge to the clinical implementation of decellularized scaffold-based tissue
engineering lies in understanding the process of removing cells and immunogenic material …
engineering lies in understanding the process of removing cells and immunogenic material …