In the last few decades extracellular vesicles (EVs), which include exosomes and
microvesicles, have attracted significant interest in cardiovascular pathophysiology due to …

The interest in non-coding RNAs, which started more than a decade ago, has still not
weakened. A wealth of experimental and clinical studies has suggested the potential of non …

Cardiovascular diseases (CVD) represent the leading cause of morbidity and mortality
globally. The emerging role of extracellular vesicles (EVs) in intercellular communication …

Urinary extracellular vesicles (uEVs) are a heterogenous group of vesicles consisting mainly
of microvesicles and exosomes that originate predominantly (99.96%) from kidney, the …

The inclusion of microRNAs (miRNAs) in extracellular microvesicles/exosomes (named
cardiosomes when deriving from cardiomyocytes) allows their active transportation and …

Heart diseases are the primary cause of mortality and morbidity worldwide which inflict a
heavy social and economic burden. Among heart diseases, most deaths are due to …

Heart failure with reduced ejection fraction (HFrEF) is defined by an ejection fraction (EF)
below 40%. Many distinct disease processes culminate in HFrEF, among them acute and …

Aims Female sex has been proposed to be cardioprotective per se. Studies with myocardial
ischaemia/reperfusion and infarct size as endpoint have demonstrated cardioprotection in …

Ischemic diseases in an aging population pose a heavy social encumbrance. Moreover,
current therapeutic approaches, which aimed to prevent or minimize ischemia-induced …

Cardiovascular diseases (CVDs) are the leading cause of human death worldwide.
Exosomes act as endogenous biological vectors; they possess advantages of low …