Spreading depression, spreading depolarizations, and the cerebral vasculature
C Ayata, M Lauritzen - Physiological reviews, 2015 - journals.physiology.org
Spreading depression (SD) is a transient wave of near-complete neuronal and glial
depolarization associated with massive transmembrane ionic and water shifts. It is …
depolarization associated with massive transmembrane ionic and water shifts. It is …
Delayed cerebral ischaemia after subarachnoid haemorrhage: looking beyond vasospasm
MJ Rowland, G Hadjipavlou, M Kelly… - British journal of …, 2012 - academic.oup.com
Despite improvements in the clinical management of aneurysmal subarachnoid
haemorrhage over the last decade, delayed cerebral ischaemia (DCI) remains the single …
haemorrhage over the last decade, delayed cerebral ischaemia (DCI) remains the single …
[HTML][HTML] Spreading depolarization is not an epiphenomenon but the principal mechanism of the cytotoxic edema in various gray matter structures of the brain during …
JP Dreier, CL Lemale, V Kola, A Friedman… - …, 2018 - Elsevier
Spreading depolarization (SD) is a phenomenon of various cerebral gray matter structures
that only occurs under pathological conditions. In the present paper, we summarize the …
that only occurs under pathological conditions. In the present paper, we summarize the …
Spreading depolarizations cycle around and enlarge focal ischaemic brain lesions
H Nakamura, AJ Strong, C Dohmen, OW Sakowitz… - Brain, 2010 - academic.oup.com
How does infarction in victims of stroke and other types of acute brain injury expand to its
definitive size in subsequent days? Spontaneous depolarizations that repeatedly spread …
definitive size in subsequent days? Spontaneous depolarizations that repeatedly spread …
Neurovascular mechanisms of migraine and cluster headache
J Hoffmann, SM Baca… - Journal of Cerebral Blood …, 2019 - journals.sagepub.com
Vascular theories of migraine and cluster headache have dominated for many years the
pathobiological concept of these disorders. This view is supported by observations that …
pathobiological concept of these disorders. This view is supported by observations that …
Cortical spreading depression as a target for anti-migraine agents
Spreading depression (SD) is a slowly propagating wave of neuronal and glial
depolarization lasting a few minutes, that can develop within the cerebral cortex or other …
depolarization lasting a few minutes, that can develop within the cerebral cortex or other …
Fiber-based electrochemical biosensors for monitoring pH and transient neurometabolic lactate
Developing tools that are able to monitor transient neurochemical dynamics is important to
decipher brain chemistry and function. Multifunctional polymer-based fibers have been …
decipher brain chemistry and function. Multifunctional polymer-based fibers have been …
Estrogen modulation of cortical spreading depression
C Kudo, AM Harriott, MA Moskowitz, C Waeber… - The journal of headache …, 2023 - Springer
Background and aims Cortical spreading depression (CSD), a transient neuronal and glial
depolarization that propagates slowly across the cerebral cortex, is the putative …
depolarization that propagates slowly across the cerebral cortex, is the putative …
Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice
K Eikermann-Haerter, I Yuzawa, T Qin… - Journal of …, 2011 - Soc Neuroscience
Familial hemiplegic migraine type 1, a monogenic migraine variant with aura, is linked to
gain-of-function mutations in the CACNA1A gene encoding CaV2. 1 channels. The S218L …
gain-of-function mutations in the CACNA1A gene encoding CaV2. 1 channels. The S218L …
Spreading depression as an innate antiseizure mechanism
I Tamim, DY Chung, AL de Morais, ICM Loonen… - Nature …, 2021 - nature.com
Spreading depression (SD) is an intense and prolonged depolarization in the central
nervous systems from insect to man. It is implicated in neurological disorders such as …
nervous systems from insect to man. It is implicated in neurological disorders such as …