Simple Summary Locally advanced vulvar cancer (LAVC) requires a multidisciplinary
management. The aim of this paper is to conduct a review of all relevant studies regarding …

Background As part of its mission to improve the quality of care for women with
gynecological cancers across Europe, the European Society of Gynaecological Oncology …

PURPOSE Treatment of vulvar carcinoma (VC) is challenging. The objectives of this review
were to describe for clinicians the epidemiologic and clinical aspects of VC, the standard of …

Evidence was searched in the Cochrane Central Register of Controlled Trials (CENTRAL,
The Cochrane Library April 2022, Issue 4), MEDLINE and EMBASE up to April 2022, with …

Background: Lymph node metastasis in vulvar cancer is a critical prognostic factor
associated with higher recurrence and decreased survival. A survival benefit is reported with …

Purpose In studies evaluating the benefit of adjuvant therapies, immortal time bias (ITB) can
affect the results by incorrectly reporting a survival advantage. It does so by including all …

Objective Most guidelines advise no adjuvant radiotherapy in vulvar squamous cell
carcinoma and a single occult intracapsular lymph node metastasis. However, several …

Purpose Vulvar squamous cell carcinoma (VSCC) is a relatively rare malignancy. Human
papillomavirus has been implicated as a causative factor for a subset of these patients. The …

Introduction Multidisciplinary treatment strategy involving adjuvant radiotherapy for
advanced vulvar cancer could be useful in offering the best personalized clinical approach …

Primary vulvar carcinomas are rare gynaecological cancers, for which surgery is the
mainstay of treatment. There is however a major place for external beam radiotherapy in the …