Bicuspid aortic valve: identifying knowledge gaps and rising to the challenge from the International Bicuspid Aortic Valve Consortium (BAVCon)

HI Michelena, SK Prakash, A Della Corte, MM Bissell… - Circulation, 2014 - Am Heart Assoc
Given the high incidence of BAV dysfunction requiring surgical intervention and the high
incidence of associated TAA formation8–10, 14–18 (Table), the BAV condition should be …

Bicuspid aortic valve disease

SC Siu, CK Silversides - Journal of the American College of Cardiology, 2010 - jacc.org
Bicuspid aortic valve (BAV) disease is the most common congenital cardiac defect. While the
BAV can be found in isolation, it is often associated with other congenital cardiac lesions …

[HTML][HTML] The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve–related aortopathy: full online-only version

MA Borger, PWM Fedak, EH Stephens… - The Journal of thoracic …, 2018 - Elsevier
Bicuspid aortic valve disease is the most common congenital cardiac disorder, being
present in 1% to 2% of the general population. Associated aortopathy is a common finding in …

ACC/AHA 2008 guidelines for the management of adults with congenital heart disease: a report of the American College of Cardiology/American Heart Association …

CA Warnes, RG Williams, TM Bashore, JS Child… - Circulation, 2008 - Am Heart Assoc
The recommendations listed in this document are, whenever possible, evidence-based.
Unlike other ACC/AHA practice guidelines, there is not a large body of peer-reviewed …

Bicuspid aortic valve is associated with altered wall shear stress in the ascending aorta

AJ Barker, M Markl, J Bürk, R Lorenz… - Circulation …, 2012 - Am Heart Assoc
Background—Hemodynamics may play a role contributing to the progression of bicuspid
aortic valve (BAV) aortopathy. This study measured the impact of BAV on the distribution of …

Vascular calcification: pathobiological mechanisms and clinical implications

RC Johnson, JA Leopold, J Loscalzo - Circulation research, 2006 - Am Heart Assoc
Once thought to result from passive precipitation of calcium and phosphate, it now appears
that vascular calcification is a consequence of tightly regulated processes that culminate in …

Prevalence of bicuspid aortic valve and associated aortopathy in newborns in Copenhagen, Denmark

AS Sillesen, O Vøgg, C Pihl, AA Raja, K Sundberg… - Jama, 2021 - jamanetwork.com
Importance The prevalence and characteristics of bicuspid aortic valve (BAV) are mainly
reported from selected cohorts. BAV is associated with aortopathy, but it is unclear if it …

Management of patients with aortic valve stenosis

A Kanwar, JJ Thaden, VT Nkomo - Mayo Clinic Proceedings, 2018 - Elsevier
With increased life expectancy and aging of the population, aortic stenosis is now one of the
most common valvular heart diseases. Early recognition and management of aortic stenosis …

Valve configuration determines long-term results after repair of the bicuspid aortic valve

D Aicher, T Kunihara, O Abou Issa, B Brittner… - Circulation, 2011 - Am Heart Assoc
Background—Reconstruction of the regurgitant bicuspid aortic valve has been performed
for> 10 years, but there is limited information on long-term results. We analyzed our results …

Ascending aortic dilatation associated with bicuspid aortic valve: pathophysiology, molecular biology, and clinical implications

TM Tadros, MD Klein, OM Shapira - Circulation, 2009 - Am Heart Assoc
BAV aortas have histopathological findings similar to those of Marfan syndrome aortas, the
underlying genetic abnormality of Marfan syndrome—mutation in the FBN1 gene that …