Dying mammalian cells emit numerous signals that interact with the host to dictate the
immunological correlates of cellular stress and death. In the absence of reactive antigenic …

Coronavirus disease 2019 (COVID-19) is a disease characterized by a profound
dysregulation of the innate immune system. This knowledge has emerged from the large …

Disease and accompanying inflammation are uncommon outcomes of viral infection in
humans. Clinical inflammation occurs if steady-state cell-intrinsic and leukocytic immunity to …

The immense interindividual clinical variability during any infection is a long-standing
enigma. Inborn errors of IFN-γ and IFN-α/β immunity underlying rare infections with weakly …

Cellular immune responses consist of innate and adaptive cell-mediated immune
mechanisms, where all leukocyte subpopulations are included. Among these are vital …

A hyperinflammatory response during severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection crucially worsens clinical evolution of coronavirus disease 2019 …

The global environment is dominated by various small exotic substances, known as
secondary metabolites, produced by plants and microorganisms. Plants and fungi are …

Type I interferon (IFN) is a class of proinflammatory cytokines with a dual role on malignant
transformation, tumor progression, and response to therapy. On the one hand, robust, acute …

Type I IFNs are so‐named because they interfere with viral infection in vertebrate cells. The
study of cellular responses to type I IFNs led to the discovery of the JAK‐STAT signaling …

The global prevalence of prediabetes is on the rise, and it is of value to manage prediabetes
and predisposal to diabetes at an early stage. Myricetin is a natural polyhydroxyflavonoid …