[HTML][HTML] The development of Gordon life science institute: its driving force and accomplishments
KC Chou - Natural Science, 2020 - scirp.org
Established in 2004, Gordon Life Science Institute is the first Internet Research Institute in
the world. It is a non-profit institute, a gift to science. Those scientists, who are really loving …
the world. It is a non-profit institute, a gift to science. Those scientists, who are really loving …
An improved deep learning model for hierarchical classification of protein families
PD Sandaruwan, CT Wannige - Plos one, 2021 - journals.plos.org
Although genes carry information, proteins are the main role player in providing all the
functionalities of a living organism. Massive amounts of different proteins involve in every …
functionalities of a living organism. Massive amounts of different proteins involve in every …
OncoRTT: Predicting novel oncology-related therapeutic targets using BERT embeddings and omics features
Late-stage drug development failures are usually a consequence of ineffective targets. Thus,
proper target identification is needed, which may be possible using computational …
proper target identification is needed, which may be possible using computational …
[HTML][HTML] Bioinformatics and machine learning driven key genes screening for hepatocellular carcinoma
Y Shen, J Huang, L Jia, C Zhang, J Xu - Biochemistry and Biophysics …, 2024 - Elsevier
Liver cancer, a global menace, ranked as the sixth most prevalent and third deadliest cancer
in 2020. The challenge of early diagnosis and treatment, especially for hepatocellular …
in 2020. The challenge of early diagnosis and treatment, especially for hepatocellular …
Use Chou's 5-steps rule to predict remote homology proteins by merging grey incidence analysis and domain similarity analysis
Detecting remote homology proteins is a challenging problem for both basic research and
drug development. Although there are a couple of methods to deal with this problem, the …
drug development. Although there are a couple of methods to deal with this problem, the …
QSAR analysis of VEGFR-2 inhibitors based on machine learning, Topomer CoMFA and molecule docking
H Ding, F Xing, L Zou, L Zhao - BMC chemistry, 2024 - Springer
VEGFR-2 kinase inhibitors are clinically approved drugs that can effectively target cancer
angiogenesis. However, such inhibitors have adverse effects such as skin toxicity …
angiogenesis. However, such inhibitors have adverse effects such as skin toxicity …
Proposing 5-steps rule is a notable milestone for studying molecular biology
KC Chou - Natural Science, 2020 - article.researchpromo.com
In this current minireview, the cradle of the “5-steps rule” or “5-step rules”, along with its
essence and advances, has been recalled. Born in 2011, its impacts on molecular biology …
essence and advances, has been recalled. Born in 2011, its impacts on molecular biology …
Some illuminating remarks on molecular genetics and genomics as well as drug development
KC Chou - Molecular Genetics and Genomics, 2020 - Springer
Facing the explosive growth of biological sequences unearthed in the post-genomic age,
one of the most important but also most difficult problems in computational biology is how to …
one of the most important but also most difficult problems in computational biology is how to …
[HTML][HTML] Other mountain stones can attack jade: the 5-steps rule
KC Chou - Natural Science, 2020 - scirp.org
Since the 5-steps rule was proposed in 2011, it has been widely used in many areas of
molecular biology, both theoretical and experimental. It can be even used to deal with the …
molecular biology, both theoretical and experimental. It can be even used to deal with the …
Using similarity software to evaluate scientific paper quality is a big mistake
KC Chou - Natural Science, 2020 - article.researchpromo.com
Using similarity software to examine the quality of scientific papers is a nuisance. The
significance of a scientific paper should be decided by the acknowledged experts. The …
significance of a scientific paper should be decided by the acknowledged experts. The …