Current developments in LC-MS for pharmaceutical analysis
M Beccaria, D Cabooter - Analyst, 2020 - pubs.rsc.org
Liquid chromatography (LC) based techniques in combination with mass spectrometry (MS)
detection have had a large impact on the development of new pharmaceuticals in the past …
detection have had a large impact on the development of new pharmaceuticals in the past …
[HTML][HTML] Metabolomics technologies for the identification and quantification of dietary phenolic compound metabolites: an overview
A López-Yerena, I Domínguez-López… - Antioxidants, 2021 - mdpi.com
In the search for natural products with properties that may protect against or slow down
chronic and degenerative diseases (eg, cancer, and cardiovascular and neurodegenerative …
chronic and degenerative diseases (eg, cancer, and cardiovascular and neurodegenerative …
[HTML][HTML] Solid phase-based microextraction techniques in therapeutic drug monitoring
S Soares, T Rosado, M Barroso, E Gallardo - Pharmaceutics, 2023 - mdpi.com
Therapeutic drug monitoring is an established practice for a small group of drugs,
particularly those presenting narrow therapeutic windows, for which there is a direct …
particularly those presenting narrow therapeutic windows, for which there is a direct …
[HTML][HTML] The second-generation antipsychotic drug aripiprazole modulates the serotonergic system in pancreatic islets and induces beta cell dysfunction in female …
D Grajales, P Vázquez, M Ruíz-Rosario, E Tudurí… - Diabetologia, 2022 - Springer
Aims/hypothesis Second-generation antipsychotic (SGA) drugs have been associated with
the development of type 2 diabetes and the metabolic syndrome in patients with …
the development of type 2 diabetes and the metabolic syndrome in patients with …
[HTML][HTML] Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via …
V Ferreira, C Folgueira, M García-Altares, M Guillén… - Redox Biology, 2023 - Elsevier
Olanzapine (OLA), a widely used second-generation antipsychotic (SGA), causes weight
gain and metabolic alterations when administered orally to patients. Recently, we …
gain and metabolic alterations when administered orally to patients. Recently, we …
Development of a trace quantitative method to investigate caffeine distribution in the Yellow and Bohai Seas, China, and assessment of its potential neurotoxic effect …
Z Yan, Y Li, A Lin, X Yang, Z Lu, H Zhang, J Tang… - Marine Pollution …, 2023 - Elsevier
Caffeine is an emerging contaminant in aquatic environments. The study utilized a validated
method to investigate the presence and distribution of caffeine in the surface water of the …
method to investigate the presence and distribution of caffeine in the surface water of the …
Electromembrane extraction of chlorprothixene, haloperidol and risperidone from whole blood and urine
X Yu, X Li, S You, Y Shi, R Zhu, Y Dong… - … of Chromatography A, 2020 - Elsevier
Separation of antipsychotic drugs from whole blood and urine is of great importance for
clinic and forensic laboratories. In this work, chlorprothixene, haloperidol and risperidone …
clinic and forensic laboratories. In this work, chlorprothixene, haloperidol and risperidone …
Determination of antipsychotic drugs in oral fluid using dried saliva spots by gas chromatography-tandem mass spectrometry
D Caramelo, T Rosado, V Oliveira, JM Rodilla… - Analytical and …, 2019 - Springer
The present work describes the optimization and validation of an analytical method for the
determination of six antipsychotic drugs (chlorpromazine, levomepromazine, cyamemazine …
determination of six antipsychotic drugs (chlorpromazine, levomepromazine, cyamemazine …
Nanoporous Ethylenediamine-Functionalized Metal–Organic Framework MIL-101 for the Removal of Proteins and Antipsychotic Drugs from Serum Samples
Z Zhang, W Han, T Lou, L Ma, W Zhou… - ACS Applied Nano …, 2022 - ACS Publications
The development of functional materials for efficient protein removal and antipsychotic drug
extraction in biological samples is attracting great interest. In this study, a nanoscale …
extraction in biological samples is attracting great interest. In this study, a nanoscale …
The effects of Aripiprazole and olanzapine on pupillary light reflex and its relationship with Pharmacogenetics in a randomized Multiple‐Dose trial
Aims Pupillography is a noninvasive and cost‐effective method to determine autonomic
nerve activity. Genetic variants in cytochrome P450 (CYP), dopamine receptor (DRD2 …
nerve activity. Genetic variants in cytochrome P450 (CYP), dopamine receptor (DRD2 …