The discovery of the iron-regulatory hormone hepcidin in 2001 has revolutionized our
understanding of iron disorders, and its measurement should advance diagnosis/treatment …

BACKGROUND The peptide hormone hepcidin plays a central role in regulating dietary iron
absorption and body iron distribution. Many human diseases are associated with alterations …

Background Current guidelines to treat iron deficiency recommend daily provision of ferrous
iron divided through the day to increase absorption. However, daily dosing and split dosing …

Iron supplements acutely increase hepcidin, but the duration and magnitude of the increase,
its dose dependence, and its effects on subsequent iron absorption have not been …

Background The most commonly used definition of iron deficiency (ID; ferritin< 100 ng/mL or
ferritin 100–300 ng/mL and transferrin saturation [TSAT]< 20%) has not been validated in …

We have investigated the precision of peptide quantitation by MALDI-TOF mass
spectrometry (MS) using six pairs of proteotypic peptides (light) and same-sequence stable …

To date, concentrations of the promising biomarker hepcidin have only been assessed in
serum of relatively small series of healthy volunteers and patients. We assessed age-and …

Anemia is highly prevalent, especially in older individuals. In selected populations, anemia
has been reported to be associated with impaired survival and health-related quality of life …

Hepcidin is a key hormone that is involved in the control of iron homeostasis in the body.
Physiologically, hepcidin is controlled by iron stores, inflammation, hypoxia, and …

Hepcidin is the master regulator of systemic iron bioavailability in humans. This review
examines primary research articles that assessed hepcidin during pregnancy and …