MYO5B and the Polygenic Landscape of Very Early-Onset Inflammatory Bowel Disease in an Ethnically Diverse Population
Background Genetic discovery in very early-onset inflammatory bowel disease (VEO-IBD)
can elucidate not only the origins of VEO-IBD, but also later-onset inflammatory bowel …
can elucidate not only the origins of VEO-IBD, but also later-onset inflammatory bowel …
Bidirectional association between inflammatory bowel disease and depression among patients and their unaffected siblings
Abstract Background and Aim Approximately 30% of inflammatory bowel disease (IBD)
patients develop depression. Conversely, several studies reported increased IBD risk …
patients develop depression. Conversely, several studies reported increased IBD risk …
Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach
Simple Summary Rheumatoid arthritis (RA) is a complex disease resulting from multiple
genetic and environmental pathogenic factors. The genetic factors include single-nucleotide …
genetic and environmental pathogenic factors. The genetic factors include single-nucleotide …
Functional analysis of novel A20 variants in patients with atypical inflammatory diseases
S Kadowaki, K Hashimoto, T Nishimura… - Arthritis Research & …, 2021 - Springer
Abstract Background A20 haploinsufficiency (HA20) is an early-onset autoinflammatory
disease caused by mutations in the TNFAIP3 gene, which encodes the protein A20 …
disease caused by mutations in the TNFAIP3 gene, which encodes the protein A20 …
A20 haploinsufficiency in a Chinese patient with intestinal behcet's disease-like symptoms: A case report
Y Chen, H Huang, Y He, M Chen, U Seidler… - Frontiers in …, 2020 - frontiersin.org
Objective: Intestinal Behcet's disease (iBD) is an autoimmune disorder diagnosed by typical
intestinal ulcers and systemic Behcet's disease (BD) manifestations. Haploinsufficiency of …
intestinal ulcers and systemic Behcet's disease (BD) manifestations. Haploinsufficiency of …
[PDF][PDF] Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach. Biology. 2021; 10 (6) …
Single-nucleotide polymorphisms (SNPs) are reported to be associated with many diseases,
including autoimmune diseases. In rheumatoid arthritis (RA), about 152 SNPs are reported …
including autoimmune diseases. In rheumatoid arthritis (RA), about 152 SNPs are reported …
A CD40 variant is associated with systemic bone loss among patients with rheumatoid arthritis
R Sghiri, H Benhassine, K Baccouche, M Ghozzi… - Clinical …, 2022 - Springer
Objectives Little is known about genes predisposing to systemic bone loss (SBL) in
rheumatoid arthritis (RA). Therefore, we examined the association between SBL and …
rheumatoid arthritis (RA). Therefore, we examined the association between SBL and …
[PDF][PDF] Eculizumab come trattamento di salvataggio nella microangiopatia trombotica secondaria a lupus eritematoso sistemico: case report e revisione della …
FM Fani, A Patera, M Delsante, GM Rossi, L Manenti… - giornaleitalianodinefrologia.it
La microangiopatia trombotica (TMA) rappresenta una grave e frequente complicanza del
lupus eritematoso sistemico (LES) ed è descritta nel 20-25% delle biopsie renali di pazienti …
lupus eritematoso sistemico (LES) ed è descritta nel 20-25% delle biopsie renali di pazienti …