Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs)
are widely expressed and have key roles in gene regulation. Recent studies have begun to …

Cancer is difficult to cure due to frequent metastasis, and developing effective therapeutic
approaches to treat cancer is urgently important. Long non-coding RNAs (lncRNAs) have …

For decades, research into cancer biology focused on the involvement of protein-coding
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …

Circular RNAs (circRNAs) are identified as vital regulators in a variety of cancers. However,
the role of circRNA in lung squamous cell carcinoma (LUSC) remains largely unknown …

The development and application of whole genome sequencing technology has greatly
broadened our horizons on the capabilities of long non-coding RNAs (lncRNAs). LncRNAs …

To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered
through functional genomics studies. Importantly, lncRNAs have been shown, in many …

Although some long noncoding (lnc) RNAs are known since the 1950s, the past 25 years
have uncovered myriad lncRNAs with diverse sequences, structures, and functions. The …

Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …

The major function of Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is to
regulate cell metabolism. However, emerging evidence indicates that IGF2BP2 plays a role …

Advances in RNA-sequencing techniques have led to the discovery of thousands of non-
coding transcripts with unknown function. There are several types of non-coding linear …