Multicomponent reactions have gained significant importance as a tool for the synthesis of a
wide variety of useful compounds, including pharmaceuticals. In this context, the multiple …

New types of Lewis acids as water-compatible catalysts have been developed. Various
metal salts were found to work as Lewis acid catalysts in aqueous media, and catalytic …

The Kabachnik–Fields (phospha-Mannich) reaction involving the condensation of primary or
secondary amines, oxo compounds (aldehydes and ketones) and> P (O) H species …

An indium (III) chloride catalyzed Biginelli reaction of 1, 3-dicarbonyl compounds,
aldehydes, and ureas offers an easy access to a broad range of dihydropyrimidin-2 (1H) …

1. Introduction a-Aminoalkylphosphonic acids 1 are structurally analogous to a-amino acids
2, obtained by isosteric substitution of the planar and less bulky carboxylic acid (CO2H) by a …

Low sensitivity toward traces of moisture and high tolerance of different functional groups
make indium tribromide suitable for carrying out multistep synthetic sequences. In particular …

In this review, recent advances in catalytic asymmetric hydrophosphonylation of aldehydes
and imines are discussed. We also summarize several proposed mechanisms for the …

Three component coupling catalyzed by TaCl5–SiO2: synthesis of α-amino phosphonates -
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Abstract 240 Years have passed since the discovery of elemental phosphorus. During that
time organophosphorus chemistry has emerged as an interesting and exciting field of …

In this study, we used a solution of FeCl3 in THF to facilitate the Mannich-type reaction of
aldehyde, amine and phosphite compounds to form corresponding α-aminophosphonates in …