Epigenetics including DNA and RNA modifications have always been the hotspot field of life
sciences in the post-genome era. Since the first mapping of N6-methyladenosine (m6A) and …

Cancer is one of the major diseases threatening human life and health worldwide.
Epigenetic modification refers to heritable changes in the genetic material without any …

Hepatocellular carcinoma (HCC) is a highly mortal type of primary liver cancer. Abnormal
epigenetic modifications are present in HCC, and RNA modification is dynamic and …

RNA modifications have emerged as important mechanisms of gene regulation.
Developmental, metabolic, and cell cycle regulatory processes are all affected by …

The role of 5-methylcytosine (m5C) in tumor initiation and progression has been
increasingly recognized. However, the precise association between the regulation of m5C …

RNA modification plays an important role in epigenetics at the posttranscriptional level, and
5-methylcytosine (m5C) has attracted increasing attention in recent years due to the …

Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer with
a poor prognosis. 5-methylcytosine (m5C) modification plays a nonnegligible role in tumor …

RNA methylation is widespread in nature. Abnormal expression of proteins associated with
RNA methylation is strongly associated with a number of human diseases including cancer …

Recently, epigenetics showed essential roles in tumour microenvironment (TME) and
immunotherapy response, however, the functions of RNA 5‐methylcytosine (m5C) …

Background Immunotherapy is a promising anti-cancer strategy in hepatocellular carcinoma
(HCC). However, a limited number of patients can benefit from it. There are currently no …