CMV and natural killer cells: shaping the response to vaccination
Cytomegaloviruses (CMVs) are highly prevalent, persistent human pathogens that not only
evade but also shape our immune responses. Natural killer (NK) cells play an important role …
evade but also shape our immune responses. Natural killer (NK) cells play an important role …
Dual role of natural killer cells on graft rejection and control of cytomegalovirus infection in renal transplantation
M López-Botet, C Vilches, D Redondo-Pachón… - Frontiers in …, 2017 - frontiersin.org
Allograft rejection constitutes a major complication of solid organ transplantation requiring
prophylactic/therapeutic immunosuppression, which increases susceptibility of patients to …
prophylactic/therapeutic immunosuppression, which increases susceptibility of patients to …
Biology and clinical relevance of HCMV-associated adaptive NK cells
F Gao, Z Zhou, Y Lin, G Shu, G Yin… - Frontiers in Immunology, 2022 - frontiersin.org
Natural killer (NK) cells are an important component of the innate immune system due to
their strong ability to kill virally infected or transformed cells without prior exposure to the …
their strong ability to kill virally infected or transformed cells without prior exposure to the …
Natural killer cells, aging, and vaccination
Aging is associated with changes in the immune system. Both (innate and adaptive) arms of
the immune system are involved. Natural killer (NK) cells are part of the innate immune …
the immune system are involved. Natural killer (NK) cells are part of the innate immune …
Expression of leukocyte immunoglobulin-like receptor subfamily B expression on immune cells in hepatocellular carcinoma
J Fan, J Li, J Han, Y Zhang, A Gu, F Song, J Duan… - Molecular …, 2021 - Elsevier
Highlights•We assessed LILRB family expression on immune cells from peripheral blood
and tumor tissues in HCC patients.•The expression of LILRB1, LILRB2 and LILRB3 in …
and tumor tissues in HCC patients.•The expression of LILRB1, LILRB2 and LILRB3 in …
[HTML][HTML] NK-cell responses are biased towards CD16-mediated effector functions in chronic hepatitis B virus infection
A Schuch, BF Zecher, PA Müller, MP Correia, F Daul… - Journal of …, 2019 - Elsevier
Background & Aims Phenotypic and functional natural killer (NK)-cell alterations are well
described in chronic hepatitis B virus (cHBV) infection. However, it is largely unknown …
described in chronic hepatitis B virus (cHBV) infection. However, it is largely unknown …
The evolutionary arms race between virus and NK cells: diversity enables population-level virus control
SKA Savoy, JE Boudreau - Viruses, 2019 - mdpi.com
Viruses and natural killer (NK) cells have a long co-evolutionary history, evidenced by
patterns of specific NK gene frequencies in those susceptible or resistant to infections. The …
patterns of specific NK gene frequencies in those susceptible or resistant to infections. The …
Adaptive NK Cells Rapidly Expand during Acute HIV Infection and Persist Despite Early Initiation of Antiretroviral Therapy
AC Hearps, J Zhou, PA Agius, P Ha, S Lee… - The Journal of …, 2024 - journals.aai.org
HIV is associated with NK cell dysfunction and expansion of adaptive-like NK cells that
persist despite antiretroviral therapy (ART). We investigated the timing of NK cell …
persist despite antiretroviral therapy (ART). We investigated the timing of NK cell …
CMV drives the expansion of highly functional memory T cells expressing NK‐cell receptors in renal transplant recipients
N Makwana, B Foley, S Fernandez… - European journal of …, 2017 - Wiley Online Library
Cytomegalovirus (CMV) is a common opportunistic infection encountered in renal transplant
recipients (RTRs) and may be reactivated without symptoms at any time post‐transplant. We …
recipients (RTRs) and may be reactivated without symptoms at any time post‐transplant. We …
Persistence of Activated and Adaptive-Like NK Cells in HIV+ Individuals despite 2 Years of Suppressive Combination Antiretroviral Therapy
AC Hearps, PA Agius, J Zhou, S Brunt… - Frontiers in …, 2017 - frontiersin.org
Innate immune dysfunction persists in HIV+ individuals despite effective combination
antiretroviral therapy (cART). We recently demonstrated that an adaptive-like CD56dim NK …
antiretroviral therapy (cART). We recently demonstrated that an adaptive-like CD56dim NK …