The hitchhiker's guide to flow chemistry∥
Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous
stream rather than in a flask. Flow equipment provides chemists with unique control over …
stream rather than in a flask. Flow equipment provides chemists with unique control over …
Synthesis of BODIPY dyes through postfunctionalization of the boron dipyrromethene core
Fluorophores based on the 4-bora-3a, 4a-diaza-s-indacene (aka boron dipyrromethene,
boron dipyrrin, or BODIPY) platform have found diverse applications in different fields of …
boron dipyrrin, or BODIPY) platform have found diverse applications in different fields of …
Scaffold hopping by net photochemical carbon deletion of azaarenes
Discovery chemists routinely identify purpose-tailored molecules through an iterative
structural optimization approach, but the preparation of each successive candidate in a …
structural optimization approach, but the preparation of each successive candidate in a …
Installing the “magic methyl”–C–H methylation in synthesis
D Aynetdinova, MC Callens, HB Hicks… - Chemical Society …, 2021 - pubs.rsc.org
The selective and efficient C–H methylation of sp2 and sp3 carbon centres has become a
powerful transformation in the synthetic toolbox. Due to the potential for profound changes to …
powerful transformation in the synthetic toolbox. Due to the potential for profound changes to …
Alcohols as alkylating agents in heteroarene C–H functionalization
J Jin, DWC MacMillan - Nature, 2015 - nature.com
Redox processes and radical intermediates are found in many biochemical processes,
including deoxyribonucleotide synthesis and oxidative DNA damage. One of the core …
including deoxyribonucleotide synthesis and oxidative DNA damage. One of the core …
[图书][B] Heterocyclic chemistry
JA Joule - 2020 - taylorfrancis.com
Covering the fundamentals of heterocyclic reactivity and synthesis, this book teaches the
subject in a way that is understandable to graduate students. Recognizing the level at which …
subject in a way that is understandable to graduate students. Recognizing the level at which …
Metal-free C–H alkylation of heteroarenes with alkyltrifluoroborates: a general protocol for 1°, 2° and 3° alkylation
A photoredox-catalyzed C–H functionalization of heteroarenes using a variety of primary,
secondary, and tertiary alkyltrifluoroborates is reported. Using Fukuzumi's …
secondary, and tertiary alkyltrifluoroborates is reported. Using Fukuzumi's …
Minisci reactions: Versatile CH-functionalizations for medicinal chemists
MAJ Duncton - MedChemComm, 2011 - pubs.rsc.org
The addition of a radical to a heteroaromatic base is commonly referred to as a Minsici
reaction. Such reactions constitute a broad-set of selective CH-functionalization processes …
reaction. Such reactions constitute a broad-set of selective CH-functionalization processes …
Iron-catalyzed reactions in organic synthesis
Metal complexes are essential instruments in the toolbox of organic chemists. The current
requirements for clean, fast, efficient, and selective processes have increased the demand …
requirements for clean, fast, efficient, and selective processes have increased the demand …
Late-stage C–H alkylation of heterocycles and 1, 4-quinones via oxidative homolysis of 1, 4-dihydropyridines
Á Gutiérrez-Bonet, C Remeur, JK Matsui… - Journal of the …, 2017 - ACS Publications
Under oxidative conditions, 1, 4-dihydropyridines (DHPs) undergo a homolytic cleavage,
forming exclusively a Csp3-centered radical that can engage in the C–H alkylation of …
forming exclusively a Csp3-centered radical that can engage in the C–H alkylation of …