Natural products have inspired chemists and physicians for millennia. Their rich structural
diversity and complexity has prompted synthetic chemists to produce them in the laboratory …

Glycosylation reactions mainly catalyzed by glycosyltransferases (Gts) occur almost
everywhere in the biosphere, and always play crucial roles in vital processes. In order to …

Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork Page 1
REVIEW www.rsc.org/npr | Natural Product Reports Type II polyketide synthases: gaining a …

Covering: up to the end of May 2011 Glyco (randomization/diversification) is a term that
encompasses strategies to diversify a core drug scaffold via enzymatic glycosylation to …

Advances in genomics and metabolomics have made clear in recent years that microbial
biosynthetic capacities on Earth far exceed previous expectations. This is attributable, in …

Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways -
Natural Product Reports (RSC Publishing) DOI:10.1039/B801747F Royal Society of Chemistry …

Publisher Summary This chapter describes the occurrence and synthesis of deoxy sugars.
Several deoxy sugars, notably 2-deoxy-D-erythro-pentose (2-deoxy-D-ribose)—the sugar …

This review is the third update of the original review, published in 1999, on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Anthracycline anticancer drugs doxorubicin and aclarubicin have been used in the clinic for
several decades to treat various cancers. Although closely related structures, their molecular …

Natural product glycosyltransferases: properties and applications Page 67 NATURAL PRODUCT
GLYCOSYLTRANSFERASES: PROPERTIES AND APPLICATIONS By GAVIN J. WILLIAMS and …