Microfluidic electroporation for cellular analysis and delivery

T Geng, C Lu - Lab on a Chip, 2013 - pubs.rsc.org
Electroporation is a simple yet powerful technique for breaching the cell membrane barrier.
The applications of electroporation can be generally divided into two categories: the release …

Electroporation of cells in microfluidic devices: a review

MB Fox, DC Esveld, A Valero, R Luttge… - Analytical and …, 2006 - Springer
In recent years, several publications on microfluidic devices have focused on the process of
electroporation, which results in the poration of the biological cell membrane. The devices …

Dual-drug delivery system based on hydrogel/micelle composites

L Wei, C Cai, J Lin, T Chen - Biomaterials, 2009 - Elsevier
We present a dual-drug delivery system (DDDS) of hydrogel/polypeptide micelle composites
in this work. The DDDS was constructed from aspirin (Asp) dispersed poly (vinyl …

A single cell electroporation chip

M Khine, A Lau, C Ionescu-Zanetti, J Seo, LP Lee - Lab on a Chip, 2005 - pubs.rsc.org
Increasing the cell membrane's permeability can be accomplished via single cell
electroporation. Polar substances that cannot otherwise permeate the plasma membrane …

Methods and apparatus for the manipulation of particle suspensions and testing thereof

C Ionescu-Zanetti, M Khine, M Schwartz… - US Patent …, 2012 - Google Patents
2011-07-28 Assigned to FLUXION BIOSCIENCES INC. reassignment FLUXION
BIOSCIENCES INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Nanofountain probe electroporation (NFP-E) of single cells

W Kang, F Yavari, M Minary-Jolandan… - Nano …, 2013 - ACS Publications
The ability to precisely deliver molecules into single cells is of great interest to biotechnology
researchers for advancing applications in therapeutics, diagnostics, and drug delivery …

Micro-/nanoscale electroporation

L Chang, L Li, J Shi, Y Sheng, W Lu, D Gallego-Perez… - Lab on a Chip, 2016 - pubs.rsc.org
Electroporation has been one of the most popular non-viral technologies for cell transfection.
However, conventional bulk electroporation (BEP) shows significant limitations in efficiency …

Single-cell electroporation

M Wang, O Orwar, J Olofsson, SG Weber - Analytical and bioanalytical …, 2010 - Springer
Single-cell electroporation (SCEP) is a relatively new technique that has emerged in the last
decade or so for single-cell studies. When a large enough electric field is applied to a single …

Single-cell electroporation

J Olofsson, K Nolkrantz, F Ryttsén, BA Lambie… - Current opinion in …, 2003 - Elsevier
Electroporation is a widely used method for the introduction of polar and charged agents
such as dyes, drugs, DNA, RNA, proteins, peptides, and amino acids into cells. Traditionally …

Calcium indicator loading of neurons using single-cell electroporation

T Nevian, F Helmchen - Pflügers Archiv-European Journal of Physiology, 2007 - Springer
Studies of subcellular Ca 2+ signaling rely on methods for labeling cells with fluorescent Ca
2+ indicator dyes. In this study, we demonstrate the use of single-cell electroporation for Ca …