Recent advances in Alzheimer's disease: Mechanisms, clinical trials and new drug development strategies
J Zhang, Y Zhang, J Wang, Y Xia, J Zhang… - Signal transduction and …, 2024 - nature.com
Alzheimer's disease (AD) stands as the predominant form of dementia, presenting significant
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …
Links between COVID-19 and Parkinson's disease/Alzheimer's disease: reciprocal impacts, medical care strategies and underlying mechanisms
P Huang, LY Zhang, YY Tan, SD Chen - Translational Neurodegeneration, 2023 - Springer
The impact of coronavirus disease 2019 (COVID-19) pandemic on patients with
neurodegenerative diseases and the specific neurological manifestations of COVID-19 have …
neurodegenerative diseases and the specific neurological manifestations of COVID-19 have …
ApoE4 associated with severe COVID-19 outcomes via downregulation of ACE2 and imbalanced RAS pathway
F Chen, Y Chen, Q Ke, Y Wang, Z Gong… - Journal of Translational …, 2023 - Springer
Background Recent numerous epidemiology and clinical association studies reported that
ApoE polymorphism might be associated with the risk and severity of coronavirus disease …
ApoE polymorphism might be associated with the risk and severity of coronavirus disease …
Apolipoprotein E and viral infection: Risks and Mechanisms
Apolipoprotein E (ApoE) is a multifunctional protein critical for lipid metabolism and
cholesterol homeostasis. In addition to being a well-known genetic determinant of both …
cholesterol homeostasis. In addition to being a well-known genetic determinant of both …
Amyloid precursor protein facilitates SARS-CoV-2 virus entry into cells and enhances amyloid-β-associated pathology in APP/PS1 mouse model of Alzheimer's …
J Chen, J Chen, Z Lei, F Zhang, LH Zeng, X Wu… - Translational …, 2023 - nature.com
Although there are indications of a trend towards less severe acute respiratory symptoms
and a decline in overall lethality from the novel Coronavirus Disease 2019 (COVID-19) …
and a decline in overall lethality from the novel Coronavirus Disease 2019 (COVID-19) …
COVID-19 and Alzheimer's Disease Share Common Neurological and Ophthalmological Manifestations: A Bidirectional Risk in the Post-Pandemic Future
G Amadoro, V Latina, E Stigliano, A Micera - Cells, 2023 - mdpi.com
A growing body of evidence indicates that a neuropathological cross-talk takes place
between the coronavirus disease 2019 (COVID-19)-the pandemic severe pneumonia that …
between the coronavirus disease 2019 (COVID-19)-the pandemic severe pneumonia that …
Oxylipin transport by lipoprotein particles and its functional implications for cardiometabolic and neurological disorders
Lipoprotein metabolism is critical to inflammation. While the periphery and central nervous
system (CNS) have separate yet connected lipoprotein systems, impaired lipoprotein …
system (CNS) have separate yet connected lipoprotein systems, impaired lipoprotein …
Targeted screening of genetic associations with COVID-19 susceptibility and severity
P Li, Y Ke, W Shen, S Shi, Y Wang, K Lin, X Guo… - Frontiers in …, 2022 - frontiersin.org
The COVID-19 pandemic has resulted in great morbidity and mortality worldwide and
human genetic factors have been implicated in the susceptibility and severity of COVID-19 …
human genetic factors have been implicated in the susceptibility and severity of COVID-19 …
COVID-19 and the cardiovascular system: a study of pathophysiology and interpopulation variability
Y Zhao, X Han, C Li, Y Liu, J Cheng… - Frontiers in …, 2023 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in humans
can lead to various degrees of tissue and organ damage, of which cardiovascular system …
can lead to various degrees of tissue and organ damage, of which cardiovascular system …
Human genetic basis of severe or critical illness in COVID-19
XS Ji, B Chen, B Ze, WH Zhou - Frontiers in cellular and infection …, 2022 - frontiersin.org
Coronavirus Disease 2019 (COVID-19) caused by the novel severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has led to considerable morbidity and mortality …
syndrome coronavirus 2 (SARS-CoV-2) has led to considerable morbidity and mortality …