The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

Antimicrobial peptides (AMPs) are molecules with a broad-spectrum activity against
bacteria, fungi, protozoa, and viruses. These peptides are widely distributed in insects …

Among the most potent and proteolytically resistant antimicrobial peptides (AMPs) of animal
origin are molecules forming a β-hairpin structure stabilized by disulfide bonds. In this study …

Protegrin-1 (PG-1) is a cationic β-hairpin pore-forming antimicrobial peptide having a
membranolytic mechanism of action. It possesses in vitro a potent antimicrobial activity …

Marine polychaetes represent an extremely rich and underexplored source of novel families
of antimicrobial peptides (AMPs). The rapid development of next generation sequencing …

The antimicrobial resistance crisis along with challenges of antimicrobial discovery revealed
the vital necessity to develop new antibiotics. Many of the animal proline-rich antimicrobial …

Endogenous antimicrobial peptides (AMPs) are evolutionary ancient molecular factors of
innate immunity that play a key role in host defense. Among the most active and stable …

Proline-rich antimicrobial peptides (PR-AMPs) having a potent antimicrobial activity
predominantly toward Gram-negative bacteria and negligible toxicity toward host cells, are …

Pediocin-like bacteriocins are among the natural antimicrobial agents attracting attention as
scaffolds for the development of a new generation of antibiotics. Acidocin A has significant …

Background: Antimicrobial resistance (AMR) to conventional antibiotics is becoming one of
the main global health threats and novel alternative strategies are urging. Antimicrobial …