Role and mechanism of autophagy‐regulating factors in tumorigenesis and drug resistance
RM Usman, F Razzaq, A Akbar… - Asia‐Pacific Journal …, 2021 - Wiley Online Library
A hallmark feature of tumorigenesis is uncontrolled cell division. Autophagy is regulated by
more than 30 genes and it is one of several mechanisms by which cells maintain …
more than 30 genes and it is one of several mechanisms by which cells maintain …
Biological actions of the Hsp90-binding immunophilins FKBP51 and FKBP52
NR Zgajnar, SA De Leo, CM Lotufo, AG Erlejman… - Biomolecules, 2019 - mdpi.com
Immunophilins are a family of proteins whose signature domain is the peptidylprolyl-
isomerase domain. High molecular weight immunophilins are characterized by the …
isomerase domain. High molecular weight immunophilins are characterized by the …
HSP90AB1: Helping the good and the bad
M Haase, G Fitze - Gene, 2016 - Elsevier
HSP90AB1 (heat shock protein 90 kDA alpha, class B, member 1), also known as
HSP90beta, is a member of the large family of HSPs which function as molecular …
HSP90beta, is a member of the large family of HSPs which function as molecular …
NF-κB transcriptional activity is modulated by FK506-binding proteins FKBP51 and FKBP52: a role for peptidyl-prolyl isomerase activity
AG Erlejman, SA De Leo, GI Mazaira… - Journal of Biological …, 2014 - ASBMB
Hsp90 binding immunophilins FKBP51 and FKBP52 modulate steroid receptor trafficking
and hormone-dependent biological responses. With the purpose to expand this model to …
and hormone-dependent biological responses. With the purpose to expand this model to …
The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative …
Confocal microscopy images revealed that the tetratricopeptide repeat motif (TPR) domain
immunophilin FKBP51 shows colocalization with the specific mitochondrial marker …
immunophilin FKBP51 shows colocalization with the specific mitochondrial marker …
Subcellular rearrangement of hsp90‐binding immunophilins accompanies neuronal differentiation and neurite outgrowth
HR Quintá, D Maschi, C Gomez‐Sanchez… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 115, 716–734. Abstract FKBP51 and FKBP52 (FK506‐binding protein
51 and 52) are tetratricopeptide repeat‐domain immunophilins belonging to the …
51 and 52) are tetratricopeptide repeat‐domain immunophilins belonging to the …
Regulatory role of the 90-kDa-heat-shock protein (Hsp90) and associated factors on gene expression
AG Erlejman, M Lagadari, J Toneatto… - … et Biophysica Acta (BBA …, 2014 - Elsevier
The term molecular chaperone was first used to describe the ability of nucleoplasmin to
prevent the aggregation of histones with DNA during the assembly of nucleosomes …
prevent the aggregation of histones with DNA during the assembly of nucleosomes …
Regulation of the glucocorticoid response to stress‐related disorders by the Hsp90‐binding immunophilin FKBP51
NM Galigniana, LT Ballmer, J Toneatto… - Journal of …, 2012 - Wiley Online Library
J. Neurochem.(2012) 122, 4–18. Abstract Immunophilin is the collective name given to a
family of proteins that bind immunosuppressive drugs: Some immunophilins are Hsp90 …
family of proteins that bind immunosuppressive drugs: Some immunophilins are Hsp90 …
Proof that the high molecular weight immunophilin FKBP52 mediates the in vivo neuroregenerative effect of the macrolide FK506
C Daneri-Becerra, MG Patiño-Gaillez… - Biochemical …, 2020 - Elsevier
The immunosuppressant drug FK506 (or tacrolimus) is a macrolide that binds selectively to
immunophilins belonging to the FK506-binding protein (FKBP) subfamily, which are …
immunophilins belonging to the FK506-binding protein (FKBP) subfamily, which are …
The landscape and prognostic value of immune characteristics in uterine corpus endometrial cancer
W Liu, L Sun, J Zhang, W Song, M Li… - Bioscience …, 2021 - portlandpress.com
In the present study, we explored the clinical and immunological characteristics of 575
uterine corpus endometrial carcinoma (UCEC) samples obtained from The Cancer Genome …
uterine corpus endometrial carcinoma (UCEC) samples obtained from The Cancer Genome …