Salivary gland macrophages and tissue-resident CD8+ T cells cooperate for homeostatic organ surveillance
It is well established that tissue macrophages and tissue-resident memory CD8+ T cells
(TRM) play important roles for pathogen sensing and rapid protection of barrier tissues. In …
(TRM) play important roles for pathogen sensing and rapid protection of barrier tissues. In …
Exocrine gland–resident memory CD8+ T cells use mechanosensing for tissue surveillance
N Ruef, J Martínez Magdaleno, X Ficht… - Science …, 2023 - science.org
Tissue-resident CD8+ T cells (TRM) continuously scan peptide-MHC (pMHC) complexes in
their organ of residence to intercept microbial invaders. Recent data showed that TRM …
their organ of residence to intercept microbial invaders. Recent data showed that TRM …
Dynamic spherical harmonics approach for shape classification of migrating cells
Cell migration involves dynamic changes in cell shape. Intricate patterns of cell shape can
be analyzed and classified using advanced shape descriptors, including spherical …
be analyzed and classified using advanced shape descriptors, including spherical …
Microbial uptake in oral mucosa–draining lymph nodes leads to rapid release of cytotoxic CD8+ T cells lacking a gut-homing phenotype
J Barreto de Albuquerque, LM Altenburger, J Abe… - Science …, 2022 - science.org
The gastrointestinal (GI) tract constitutes an essential barrier against ingested microbes,
including potential pathogens. Although immune reactions are well studied in the lower GI …
including potential pathogens. Although immune reactions are well studied in the lower GI …
Advances and challenges in intravital imaging of craniofacial and dental progenitor cells
Craniofacial and appendicular bone homeostasis is dynamically regulated by a balance
between bone formation and resorption by osteoblasts and osteoclasts, respectively …
between bone formation and resorption by osteoblasts and osteoclasts, respectively …
Interrogating Cell-Cell Interactions in the Salivary Gland via Ex Vivo Live Cell Imaging
S Elder, J Cholewa-Waclaw… - JoVE (Journal of Visualized …, 2023 - app.jove.com
Salivary gland regeneration is a complex process involving intricate interactions among
various cell types. Recent studies have shed light on the pivotal role played by …
various cell types. Recent studies have shed light on the pivotal role played by …
A Novel Experimental Approach for In Vivo Analyses of the Salivary Gland Microvasculature
B Uhl, C Braun, J Dominik, J Luft, M Canis… - Frontiers in …, 2021 - frontiersin.org
Microvascular dysfunction plays a fundamental role in the pathogenesis of salivary gland
disorders. Restoring and preserving microvascular integrity might therefore represent a …
disorders. Restoring and preserving microvascular integrity might therefore represent a …
CD8+ T cell priming in oral mucosa-draining lymph nodes supports systemic immunity
JB de Albuquerque, D von Werdt, D Francisco… - bioRxiv, 2020 - biorxiv.org
The gastrointestinal (GI) tract constitutes an essential barrier against ingested pathogens.
While immune reactions are well-studied in the lower GI tract, it remains unclear how …
While immune reactions are well-studied in the lower GI tract, it remains unclear how …
Salivary gland macrophages assist tissue-resident CD8+ T cell immune surveillance
Tissue macrophages and tissue resident memory CD8+ T cells (TRM) play important roles
for pathogen sensing and rapid protection of barrier tissues. To date, it is incompletely …
for pathogen sensing and rapid protection of barrier tissues. To date, it is incompletely …