DNA origami

S Dey, C Fan, KV Gothelf, J Li, C Lin, L Liu… - Nature Reviews …, 2021 - nature.com
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

Design and simulation of DNA, RNA and hybrid protein–nucleic acid nanostructures with oxView

J Bohlin, M Matthies, E Poppleton, J Procyk, A Mallya… - Nature protocols, 2022 - nature.com
Molecular simulation has become an integral part of the DNA/RNA nanotechnology
research pipeline. In particular, understanding the dynamics of structures and single …

OxDNA. org: a public webserver for coarse-grained simulations of DNA and RNA nanostructures

E Poppleton, R Romero, A Mallya… - Nucleic acids …, 2021 - academic.oup.com
OxDNA and oxRNA are popular coarse-grained models used by the DNA/RNA
nanotechnology community to prototype, analyze and rationalize designed DNA and RNA …

Advanced applications of DNA nanostructures dominated by DNA origami in antitumor drug delivery

Y Zhang, X Tian, Z Wang, H Wang, F Liu… - Frontiers in Molecular …, 2023 - frontiersin.org
DNA origami is a cutting-edge DNA self-assembly technique that neatly folds DNA strands
and creates specific structures based on the complementary base pairing principle. These …

Cascaded enzyme reactions over a three-dimensional, wireframe DNA origami scaffold

JS Kahn, Y Xiong, J Huang, O Gang - Jacs Au, 2022 - ACS Publications
DNA nanotechnology has increasingly been used as a platform to scaffold enzymes based
on its unmatched ability to structure enzymes in a desired format. The capability to organize …

[HTML][HTML] The art of designing DNA nanostructures with CAD software

M Glaser, S Deb, F Seier, A Agrawal, T Liedl… - Molecules, 2021 - mdpi.com
Since the arrival of DNA nanotechnology nearly 40 years ago, the field has progressed from
its beginnings of envisioning rather simple DNA structures having a branched, multi-strand …

Scadnano: A browser-based, scriptable tool for designing DNA nanostructures

D Doty, BL Lee, T Stérin - arXiv preprint arXiv:2005.11841, 2020 - arxiv.org
We introduce $\textit {scadnano} $(https://scadnano. org)(short for" scriptable cadnano"), a
computational tool for designing synthetic DNA structures. Its design is based heavily on …

Increasing complexity in wireframe DNA nanostructures

P Piskunen, S Nummelin, B Shen, MA Kostiainen… - Molecules, 2020 - mdpi.com
Structural DNA nanotechnology has recently gained significant momentum, as diverse
design tools for producing custom DNA shapes have become more and more accessible to …

ENSnano: a 3D modeling software for DNA nanostructures

N Levy, N Schabanel - DNA27-27th International Conference on DNA …, 2021 - hal.science
Since the 1990s, increasingly complex nanostructures have been reliably obtained out of
self-assembled DNA strands: from" simple" 2D shapes to 3D gears and articulated nano …

DNA nanodevices as mechanical probes of protein structure and function

N Stephanopoulos, P Šulc - Applied Sciences, 2021 - mdpi.com
DNA nanotechnology has reported a wide range of structurally tunable scaffolds with
precise control over their size, shape and mechanical properties. One promising application …