High rates of failure, exorbitant costs, and the sluggish pace of new drug discovery and
development have led to a growing interest in repurposing “old” drugs to treat both common …

Introduction Drugs that prevent the onset, slow progression, or improve cognitive and
behavioral symptoms of Alzheimer's disease (AD) are needed. Methods We searched …

Chagas disease is a vector-borne illness caused by the protozoan parasite Trypanosoma
cruzi (T. cruzi). It poses a significant public health burden, particularly in the poorest regions …

Resistance to antibiotic treatment developed by bacteria in humans and animals occurs
when the microorganisms resist treatment with clinically approved antibiotics. Actions must …

Introduction Drugs that have demonstrated good activity against any member of the
Orthopoxvirus genus are good candidates for repurposing studies against the mpox virus …

Drug repurposing in glomerular disease can deliver opportunities for steroid-free regimens,
enable personalized multi-target options for resistant or relapsing disease and enhance …

In women, cervical cancer (CC) is the fourth most common cancer around the world with
average cases of 604,000 and 342,000 deaths per year. Approximately 50% of high-grade …

Cancer represents the main cause of death worldwide. Thyroid cancer (TC) shows an
overall good rate of survival, however there is a percentage of patients that do not respond …

The growing prevalence of MDR and XDR bacterial pathogens is posing a critical threat to
global health. Traditional antibiotic development paths have encountered significant …

In recent years, developing the idea of “cancer big data” has emerged as a result of the
significant expansion of various fields such as clinical research, genomics, proteomics and …