This paper addresses how long lifespan can be extended via multiple interventions, such as
dietary supplements [eg, curcumin, resveratrol, sulforaphane, complex phytochemical …

Many organisms have stress response pathways, components of which share homology
with players in complex human disease pathways. Research on stress response in the …

Research programmes on oxidative stress and hormesis are wide ranging. Biomedical and
toxicological sciences have traditionally centralised such research, but in the last years we …

Although many studies have examined quantitative trait variation across many species, only
a small number of genes and thereby molecular mechanisms have been discovered …

Differential antioxidant action is found upon comparison of organ/tissue systems in the
human body. In erythrocytes (red blood cells), which transport oxygen and carbon dioxide …

Antioxidant action to afford a health benefit or increased well-being may not be directly
exerted by quick reduction-oxidation (REDOX) reactions between the antioxidant and the …

Predicting phenotype from genotype is greatly complicated by the polygenic nature of most
traits and by the complex interactions between phenotype and the environment. Here, we …

Researchers are increasingly focused on the nanoscale level of organization where
biological processes take place in living systems. Nanoparticles (NPs, eg, 1–100 nm …

Changes in intracellular reactive oxygen species (ROS) levels due to remodeling of
antioxidant defense can affect the status of biological homeostasis in aging/oxidative stress …

There is considerable insight into pathways and genes associated with heat-stress
conditions. Most genes involved in stress response have been identified using mutant …