What are reactive oxygen species, free radicals, and oxidative stress in skin diseases?

K Nakai, D Tsuruta - International journal of molecular sciences, 2021 - mdpi.com
Oxygen in the atmosphere is a crucial component for life-sustaining aerobic respiration in
humans. Approximately 95% of oxygen is consumed as energy and ultimately becomes …

[HTML][HTML] Pathogenesis of IgA vasculitis: an up-to-date review

Y Song, X Huang, G Yu, J Qiao, J Cheng, J Wu… - Frontiers in …, 2021 - frontiersin.org
Immunoglobin A (IgA) vasculitis (IgAV), formerly called the Henoch-Schönlein purpura
(HSP), is a small vessel vasculitis, characterized by IgA1-dominant immune deposition at …

The neutrophil: A key resourceful agent in immune‐mediated vasculitis

K Aymonnier, J Amsler, P Lamprecht… - Immunological …, 2023 - Wiley Online Library
The term “vasculitis” refers to a group of rare immune‐mediated diseases characterized by
the dysregulated immune system attacking blood vessels located in any organ of the body …

Role of neutrophils in systemic vasculitides

D Michailidou, T Mustelin, C Lood - Frontiers in Immunology, 2020 - frontiersin.org
Neutrophils and neutrophil extracellular traps (NETs) contribute to the pathogenesis of many
autoimmune diseases, including vasculitis. Though neutrophils, and NETs, can break self …

Immunoregulation and clinical significance of neutrophils/NETs-ANGPT2 in tumor microenvironment of gastric cancer

S Yang, X Zou, J Li, H Yang, A Zhang, Y Zhu… - Frontiers in …, 2022 - frontiersin.org
Although significant progress has been made in the study of gastric cancer (GC), clinicians
lack reliable protein markers for accurate diagnosis and tumor stratification. Neutrophil …

The Involvement of neutrophil extracellular traps in disease activity associated with IgA vasculitis

XQ Chen, L Tu, JS Zou, SQ Zhu, YJ Zhao… - Frontiers in …, 2021 - frontiersin.org
Objectives This aim of this study was to determine whether neutrophil extracellular traps
(NETs) are involved in the pathogenesis of IgA vasculitis (IgAV) and investigate whether the …

Neutrophil extracellular traps involved in the pathogenesis of IgA vasculitis: Confirmed in two IgAV rat models

XQ Chen, JS Zou, L Tu, X Yun, YH Qin - PLoS One, 2023 - journals.plos.org
Background Neutrophil extracellular traps (NETs) have been found to play a role in the
development of autoimmune diseases. In the past two years, studies have demonstrated a …

An emerging role for neutrophil extracellular traps in IgA vasculitis: a mini-review

XQ Chen, L Tu, Q Tang, L Huang, YH Qin - Frontiers in Immunology, 2022 - frontiersin.org
Immunoglobulin A vasculitis (IgAV) is the most common systemic small vessel vasculitis in
childhood. Its clinical manifestations are non-thrombocytopenic purpura, accompanied by …

DNase I targeted degradation of neutrophil extracellular traps to reduce the damage on IgAV rat

XQ Chen, L Tu, Q Tang, JS Zou, X Yun, YH Qin - Plos one, 2023 - journals.plos.org
Background In the past two years, studies have found a significant increase in neutrophil
extracellular traps (NETs) in patients with IgA vasculitis (IgAV), which is correlated with the …

Establishment of a humanized animal model of systemic sclerosis in which T helper-17 cells from patients with systemic sclerosis infiltrate and cause fibrosis in the …

MJ Park, Y Park, JW Choi, JA Baek, HY Jeong… - … & Molecular Medicine, 2022 - nature.com
Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by inflammation,
microangiopathy, and progressive fibrosis in the skin and internal organs. To evaluate the …