Human respiratory syncytial virus: pathogenesis, immune responses, and current vaccine approaches

SA Taleb, AA Al Thani, K Al Ansari… - European Journal of …, 2018 - Springer
Respiratory syncytial virus continues to pose a serious threat to the pediatric populations
worldwide. With a genomic makeup of 15,200 nucleotides, the virus encodes for 11 proteins …

Principle, application and challenges of development siRNA-based therapeutics against bacterial and viral infections: a comprehensive review

H Motamedi, MM Ari, A Alvandi, R Abiri - Frontiers in Microbiology, 2024 - frontiersin.org
While significant progress has been made in understanding and applying gene silencing
mechanisms and the treatment of human diseases, there have been still several obstacles in …

Antiviral activity of polysaccharide extract from Laminaria japonica against respiratory syncytial virus

Y Cao, Y Hao, Z Li, S Liu, L Wang - Biomedicine & Pharmacotherapy, 2016 - Elsevier
This study was designed to investigate the inhibition activity of polysaccharide extract from
Laminaria japonica against RSV. The polysaccharide from Laminaria japonica was isolated …

Progress in non-viral localized delivery of siRNA therapeutics for pulmonary diseases

J Gao, Z Xia, D Vohidova, J Joseph, JN Luo… - … Pharmaceutica Sinica B, 2023 - Elsevier
Emerging therapies based on localized delivery of siRNA to lungs have opened up exciting
possibilities for treatment of different lung diseases. Localized delivery of siRNA to lungs has …

siRNA-mediated simultaneous regulation of the cellular innate immune response and human respiratory syncytial virus replication

M Martín-Vicente, S Resino, I Martínez - Biomolecules, 2019 - mdpi.com
Human respiratory syncytial virus (HRSV) infection is a common cause of severe lower
respiratory tract diseases such as bronchiolitis and pneumonia. Both virus replication and …

Short hairpin RNA-mediated matrix gene silencing of human respiratory syncytial virus as a potent antiviral strategy

SA Zadeh Fard, H Abuei, A Farhadi, GR Dehbidi… - Future …, 2023 - Taylor & Francis
Aim: Human respiratory syncytial virus (HRSV) is a common cause of respiratory infections,
particularly in infants and the elderly. Ribavirin is the only US FDA-approved antiviral drug …

[PDF][PDF] Design of therapeutic siRNAs for SARS-CoV-2

A Salimi, T Jafarzadeh, SM Mohammadi - academia.edu
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has impressed many people in the world. Despite …

[PDF][PDF] Journal of Molecular Virology and Immunology

SA HUDU - Toxicology Research - researchgate.net
Hepatitis viruses (hepatotropic viruses) are classified into five kinds, denoted by the letters A,
B, C, D, and E, each with its own unique genotypes, clinical implications, and geographic …

[PDF][PDF] Lucas Alves Vianna

BV da Influenza - sappg.ufes.br
UNIVERSIDADE FEDERAL DO ESPÍRITO SANTO CENTRO DE CIÊNCIAS DA SAÚDE
PROGRAMA DE PÓS-GRADUAÇÃO EM BIOTECNOLOGIA Lucas Alves Page 1 …

Magnitude of RSV Fusion Protein-Specific Antibodies in Infants and Corresponding Mothers

S Taleb - 2018 - qspace.qu.edu.qa
INTRODUCTION: Respiratory syncytial virus (RSV) is a threatening agent causing lower
respiratory infections (LRI) among children, where no vaccine is available. RSV expresses …