Understanding emotions: origins and roles of the amygdala

G Šimić, M Tkalčić, V Vukić, D Mulc, E Španić, M Šagud… - Biomolecules, 2021 - mdpi.com
Emotions arise from activations of specialized neuronal populations in several parts of the
cerebral cortex, notably the anterior cingulate, insula, ventromedial prefrontal, and …

The prefrontal cortex, pathological anxiety, and anxiety disorders

MM Kenwood, NH Kalin, H Barbas - Neuropsychopharmacology, 2022 - nature.com
Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …

[HTML][HTML] Don't fear 'fear conditioning': Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear

TB Lonsdorf, MM Menz, M Andreatta… - Neuroscience & …, 2017 - Elsevier
The so-called 'replicability crisis' has sparked methodological discussions in many areas of
science in general, and in psychology in particular. This has led to recent endeavours to …

Maximizing exposure therapy: An inhibitory learning approach

MG Craske, M Treanor, CC Conway, T Zbozinek… - Behaviour research and …, 2014 - Elsevier
Exposure therapy is an effective approach for treating anxiety disorders, although a
substantial number of individuals fail to benefit or experience a return of fear after treatment …

The role of associative fear and avoidance learning in anxiety disorders: Gaps and directions for future research

A Pittig, M Treanor, RT LeBeau, MG Craske - … & Biobehavioral Reviews, 2018 - Elsevier
Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …

Fear generalization in humans: systematic review and implications for anxiety disorder research

S Dymond, JE Dunsmoor, B Vervliet, B Roche… - Behavior therapy, 2015 - Elsevier
Fear generalization, in which conditioned fear responses generalize or spread to related
stimuli, is a defining feature of anxiety disorders. The behavioral consequences of …

Anxious individuals have difficulty learning the causal statistics of aversive environments

M Browning, TE Behrens, G Jocham, JX O'reilly… - Nature …, 2015 - nature.com
Statistical regularities in the causal structure of the environment enable us to predict the
probable outcomes of our actions. Environments differ in the extent to which action-outcome …

[HTML][HTML] High anxiety trait: a vulnerable phenotype for stress-induced depression

M Weger, C Sandi - Neuroscience & Biobehavioral Reviews, 2018 - Elsevier
A great deal of research aims to identify risk factors related to individual vulnerability to
develop stress-induced psychopathologies. Here, we summarize evidence that point at …

Anxiety and decision-making

CA Hartley, EA Phelps - Biological psychiatry, 2012 - Elsevier
Although the everyday decision-making of clinically anxious individuals is clearly influenced
by their excessive fear and worry, the relationship between anxiety and decision-making …

More than just noise: Inter-individual differences in fear acquisition, extinction and return of fear in humans-Biological, experiential, temperamental factors, and …

TB Lonsdorf, CJ Merz - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Why do only some individuals develop pathological anxiety following adverse events? Fear
acquisition, extinction and return of fear paradigms serve as experimental learning models …