Frailty, a syndrome characterized by an exaggerated decline in function and reserve of
multiple physiological systems, is common in older patients with heart failure (HF) and is …

Heart failure is a clinical syndrome that affects> 6.5 million Americans, with an estimated 550
000 new cases diagnosed each year. The complexity of heart failure management is …

Aims To describe the prevalence, overlap, and prognostic implications of physical and social
frailties and cognitive dysfunction in hospitalized elderly patients with heart failure. Methods …

There is an increasing proportion of the general population surviving to old age with
significant chronic disease, multi-morbidity, and disability. The prevalence of pre-frail state …

Background Although frailty has been associated with increased risks for hospitalization and
mortality in chronic heart failure, the precise average effect remains uncertain. We performed …

Heart failure (HF) and frailty are two distinct yet commonly associated conditions. The
interplay between the two conditions is complex, due to overlaps in underlying mechanisms …

A transthoracic echocardiogram is recommended in patients with suspected heart failure, to
improve diagnostic accuracy, and in patients with a new diagnosis of heart failure, to assess …

BACKGROUND Frailty is prevalent in the patients with advanced heart failure; however, its
impact on clinical outcomes after heart transplantation (HTx) is unclear. The aim of this study …

Frailty is a complex clinical syndrome associated with ageing and chronic illness, resulting
from multiple organ impairment; physiological reserves decrease and vulnerability to …

Objectives In this study, we sought to evaluate the association of frailty with the use of
optimal guideline-directed medical therapy (GDMT) and outcomes in heart failure with …