Mitral annulus calcification (MAC) is a chronic, degenerative process in the fibrous base of
the mitral valve. Although MAC was initially thought to be an age-related degenerative …

Transcatheter mitral valve implantation (TMVI) represents a promising approach to treating
mitral valve regurgitation in patients at increased risk of perioperative mortality. Similar to …

Aims Calcified aortic stenosis (AS) and mitral annular calcification (MAC) have certain
similar etiology and pathophysiological mechanisms. MAC is frequently encountered in pre …

The mitral annulus is a fibrous structure that surrounds the mitral valve leaflets and is prone
to calcification. Despite its common occurrence, association with cardiovascular morbidity …

Background: The incidence of structural valve deterioration after bioprosthesis (BP) aortic
valve replacement (AVR) established on the basis of reoperation may substantially …

Background and aims We tested the hypotheses (i) that elevated lipoprotein (a) is causally
associated with both mitral and aortic valve calcification and disease, and (ii) that aortic …

Objective To evaluate the prevalence and natural history of mitral annulus calcification
(MAC) and associated mitral valve dysfunction (MVD) in patients undergoing clinically …

Mitral annular calcification (MAC) is a common and challenging pathologic condition,
especially in the context of an aging society. Surgical mitral valve intervention in patients …

The majority of children with congenital heart disease now live into adulthood due to the
remarkable surgical and medical advances that have taken place over the past half century …

It is known that there is an ongoing increase in life expectancy worldwide, especially in the
population older than 65 years of age. Cardiac aging is characterized by a series of complex …