Trehalose, a non-reducing disaccharide, is widespread throughout the biological world. It is
the major blood sugar in insects playing a crucial role as an instant source of energy and in …

Abstract Treatment of diabetes mellitus by oral α-glucosidase inhibitors is currently confined
to acarbose, miglitol and voglibose marred by efficacy problems and unwanted side effects …

The main objective of this review is to provide a comprehensive survey of methods used for
stereoselective construction of carbon–nitrogen bonds during the total synthesis of nitrogen …

Covering: July 2001 to December 2012 This review covers pyrrolizidine alkaloids isolated
from natural sources. Topics include: aspects of structure, isolation, and biological …

The synthesis of polyhydroxylated indolizidines and pyrrolizidines belonging to the class of
iminosugars, endowed with a vast and assorted biological activity, can be achieved in a …

We report the first attempt of double-spot structural modification on a side-chain moiety of
sulfonium-type α-glucosidase inhibitors isolated from genus Salacia. A series of sulfonium …

Abstract The Asian citrus psyllid, Diaphorina citri is the principal vector of huanglongbing,
which transmits Candidatus Liberibacter asiaticus. Trehalase is a key enzyme involved in …

Background Diabetes mellitus, notably type 2, is a rising global health challenge, prompting
the need for effective management strategies. Common medications such as metformin …

Naturally occurring pyrrolizidine alkaloids (PAs) are isolated from plants and other sources.
The interest of the scientific community in these compounds owes itself to their high toxicity …

Covering: 2005 to the end of 2009 In addition to their clinical importance in the treatment of
type II diabetes, α-glucosidase inhibitors have attracted considerable attention from the …