Oxygen is a vital source of energy necessary to sustain and complete embryonic
development. Not only is oxygen the driving force for many cellular functions and …

Bioreactors are engineered systems capable of supporting a biologically active situation for
conducting aerobic or anaerobic biochemical processes. Stability, operational ease …

Diffusion models are important in tissue engineering as they enable an understanding of
gas, nutrient, and signaling molecule delivery to cells in cell cultures and tissue constructs …

Abstract Three‐dimensional (3D) cell culture has developed rapidly over the past 5–10
years with the goal of better replicating human physiology and tissue complexity in the …

Bioreactor systems facilitate three-dimensional (3D) cell culture by coping with limitations of
static cultivation techniques. To allow for the investigation of proper cultivation conditions …

In tissue engineering and regenerative medicine, studies that utilize 3D scaffolds for
generating voluminous tissues are mostly confined in the realm of in vitro research and …

Oxygen deprivation within tumors is one of the most prevalent causes of resilient cancer cell
survival and increased immune evasion in breast cancer (BCa). Current in vitro models do …

The use of engineered cells, tissues, and organs has the opportunity to change the way
injuries and diseases are treated. Commercialization of these groundbreaking technologies …

Dynamic‐based systems are bio‐designed in order to mimic the micro‐environments of the
bone tissue. There is limited direct comparison between perfusion and perfusion‐rotation …

Bioreactor system has been used in bone tissue engineering in order to simulate dynamic
nature of bone tissue environments. Perfusion bioreactors have been reported as the most …