Acquired by inhalation of the thermal dimorphic fungi Paracoccidioides spp. conidia,
paracoccidioidomycosis ranges from symptomatic to severe and potentially fatal …

Treatment modalities for systemic mycoses are still limited. Currently, the main antifungal
therapeutics include polyenes, azoles, and echinocandins. However, even in the setting of …

Invasive mycoses are a major problem for immunocompromised individuals and patients in
intensive care units. Morbidity and mortality rates of these infections are high because of late …

Diseases caused by fungi can occur in healthy people, but immunocompromised patients
are the major risk group for invasive fungal infections. Cases of fungal resistance and the …

Currently, the significance of fungi as human pathogens is not medically concealed in the
world. Consequently, suitable recognition and treatment of such infections are of great …

Fungal diseases have been emerging as an important public health problem worldwide with
the increase in host predisposition factors due to immunological dysregulations …

Objectives In this study, polymeric nanoparticles based on chitosan incorporating the
antifungal miconazole nitrate were fabricated and tested in vivo using murine vulvovaginal …

Fungal diseases have posed a great challenge to global health, but have fewer solutions
compared to bacterial and viral infections. Development and application of new treatment …

ABSTRACT Vaccination with peptide 10 (P10), derived from the Paracoccidioides
brasiliensis glycoprotein 43 (gp43), induces a Th1 response that protects mice in an …

Mycoses are gaining increasing attention in modern medicine because of the increase in
diseases associated with opportunistic fungal infections. Despite the recognized role of the …