Wnt‐4 is expressed in developing neural and renal tissue and is required for renal
tubulogenesis in mouse and Xenopus. The function of Wnt‐4 in neural differentiation is …

NKX2. 1 is a homeodomain transcription factor that controls development of the brain, lung,
and thyroid. In the lung, Nkx2. 1 is expressed in a proximo-distal gradient and activates …

Abstract Upregulated gene 19 (U19)/ELL-associated factor 2 (Eaf2) is a potential human
tumor suppressor that exhibits frequent allelic loss and downregulation in high-grade …

Eaf family genes act in multiple cellular responses such as tumor suppression and
embryonic development. In our previous work, Eaf1/2 was found to modulate convergence …

Studies have attributed several functions to the Eaf family, including tumor suppression and
eye development. Given the potential association between cancer and development, we set …

In vertebrates, Sonic hedgehog (Shh) and transforming growth factor-β (TGF-β) signaling
pathways occur in an overlapping manner in many morphogenetic processes. In vitro data …

Inherited mitochondrial mutations can result in mitochondrial dysfunction or stochastic
oxidative damage. Cumulative mitochondrial damage is an important factor in age-related …

Skeletal muscle in the forelimb develops during embryonic and fetal development and
perinatally. While much is known regarding the molecules involved in forelimb myogenesis …

Due to the lack of sensitive biomarkers, cancer disease kill 9.6 million individuals each year
around the globe. The present study aimed to explore the association between ELL …

Complex molecular interactions dictate the developmental steps that lead to a mature and
functional cornea and lens. Peters anomaly is one subtype of anterior segment dysgenesis …