Outcomes of psychotic disorders are associated with high personal, familiar, societal and
clinical burden. There is thus an urgent clinical and societal need for improving those …

At its re-birth 30 years ago, the neurodevelopment hypothesis of schizophrenia focussed on
aberrant genes and early neural hazards, but then it grew to include ideas concerning …

The current management of patients with primary psychosis worldwide is often remarkably
stereotyped. In almost all cases an antipsychotic medication is prescribed, with second …

The long‐term benefit‐to‐risk ratio of sustained antipsychotic treatment for schizophrenia
has recently been questioned. In this paper, we critically examine the literature on the long …

The process of stopping antipsychotics may be causally related to relapse, potentially linked
to neuroadaptations that persist after cessation, including dopaminergic hypersensitivity …

Schizophrenia is associated with substantial unmet needs, highlighting the necessity for
new treatments. This narrative review compares the pharmacology, clinical trial data and …

Background Acceptance-and mindfulness-based approaches have gained popularity in
recent years. Objective A systematic review and meta-analysis of the efficacy and safety of …

Objective: It is generally believed that after the first episode of schizophrenia, the risk of
relapse decreases with time in patients who are stabilized. Many treatment guidelines …

Background The experience sampling method (ESM) builds an intensive time series of
experiences and contexts in the flow of daily life, typically consisting of around 70 reports …

This paper considers possible epistemologies for user-led and survivor research by drawing
on four discourses: the mainstream English tradition, Canadian Mad Studies, critical theory …