Fluid biomarkers in frontotemporal dementia: past, present and future

IJ Swift, A Sogorb-Esteve, C Heller… - Journal of Neurology …, 2021 - jnnp.bmj.com
The frontotemporal dementia (FTD) spectrum of neurodegenerative disorders includes a
heterogeneous group of conditions. However, following on from a series of important …

Biomarker discovery and development for frontotemporal dementia and amyotrophic lateral sclerosis

JS Katzeff, F Bright, K Phan, JJ Kril, LM Ittner… - Brain, 2022 - academic.oup.com
Frontotemporal dementia refers to a group of neurodegenerative disorders characterized by
behaviour and language alterations and focal brain atrophy. Amyotrophic lateral sclerosis is …

[HTML][HTML] Biomarkers in frontotemporal dementia: Current landscape and future directions

A Gifford, N Praschan, A Newhouse… - Biomarkers in …, 2023 - Elsevier
Frontotemporal dementia (FTD) is one of the most common neurodegenerative diseases,
encompassing a myriad of different, clinically distinct subtypes which all target the …

Voluntary wheel running is capable of improving cognitive function only in the young but not the middle-aged male APPSwe/PS1De9 mice

G Wang, HH Zhou, L Luo, LQ Qin, J Yin, Z Yu… - Neurochemistry …, 2021 - Elsevier
To determine whether voluntary wheel running could improve cognitive function from both
the young and middle-aged APP/PS1 mice and the underlying mechanisms involved in …

Systematic review: genetic, neuroimaging, and fluids biomarkers for frontotemporal dementia across Latin America countries

C Duran-Aniotz, P Orellana, T Leon Rodriguez… - Frontiers in …, 2021 - frontiersin.org
Frontotemporal dementia (FTD) includes a group of clinically, genetically, and pathologically
heterogeneous neurodegenerative disorders, affecting the fronto-insular-temporal regions of …

[HTML][HTML] Brain regions show different metabolic and protein arginine methylation phenotypes in frontotemporal dementias and Alzheimer's disease

F Zhang, A Rakhimbekova, T Lashley, T Madl - Progress in Neurobiology, 2023 - Elsevier
Frontotemporal dementia (FTD) is a heterogeneous neurodegenerative disease with
multiple histopathological subtypes. FTD patients share similar symptoms with Alzheimer's …

Plasmalogens improve swimming performance by modulating the expression of genes involved in amino acid and lipid metabolism, oxidative stress, and ferroptosis in …

J Feng, G Song, Y Wu, X Chen, J Pang, Y Xu… - Food & Function, 2021 - pubs.rsc.org
Plasmalogens (PLs) are critical to human health. Studies have reported a link between the
downregulation of PLs levels and cognitive impairments in patients with Alzheimer's disease …

Metabolomic analysis of aqueous humor identifies aberrant amino acid and fatty acid metabolism in Vogt-Koyanagi-Harada and Behcet's disease

J Xu, G Su, X Huang, R Chang, Z Chen, Z Ye… - Frontiers in …, 2021 - frontiersin.org
To investigate aqueous metabolic profiles in Vogt-Koyanagi-Harada (VKH) and Behcet's
disease (BD), we applied ultra-high-performance liquid chromatography equipped with …

[HTML][HTML] Chronic treatment with baicalein alleviates behavioural disorders and improves cerebral blood flow via reverting metabolic abnormalities in a J20 transgenic …

L Zhang, LR Wong, P Wong, W Shen, S Yang… - Brain, Behavior, & …, 2023 - Elsevier
Baicalein (BE) has both antioxidant and anti-inflammatory effects. It has also been reported
able to improve cerebral blood circulation in brain ischemic injury. However, its chronic …

The associations of serum valine with mild cognitive impairment and Alzheimer's disease

Y Xiong, J Therriault, S Ren, X Jing, H Zhang… - Aging Clinical and …, 2022 - Springer
Background The introduction of metabolomics makes it possible to study the characteristic
changes of peripheral metabolism in Alzheimer's disease (AD). Recent studies have found …