[HTML][HTML] An overview of Acinetobacter baumannii pathogenesis: Motility, adherence and biofilm formation

HJ Mea, PVC Yong, EH Wong - Microbiological research, 2021 - Elsevier
The Gram-negative opportunistic pathogen Acinetobacter baumannii has gain notoriety in
recent decades, primarily due to its propensity to cause nosocomial infections in critically ill …

Virulence Potential and Treatment Options of Multidrug-Resistant (MDR) Acinetobacter baumannii

S Kumar, R Anwer, A Azzi - Microorganisms, 2021 - mdpi.com
Acinetobacter baumannii is an opportunistic pathogen which is undoubtedly known for a
high rate of morbidity and mortality in hospital-acquired infections. A. baumannii causes life …

Nasopharyngeal microbiome of COVID-19 patients revealed a distinct bacterial profile in deceased and recovered individuals

D Kumar, R Pandit, S Sharma, J Raval, Z Patel… - Microbial …, 2022 - Elsevier
The bacterial co-infections in SARS-CoV-2 patients remained the least explored subject of
clinical manifestations that may also determine the disease severity. Nasopharyngeal …

[HTML][HTML] Developing new therapeutic approaches for treating infections caused by multi-drug resistant Acinetobacter baumannii: Acinetobacter baumannii therapeutics

P Gallagher, S Baker - Journal of Infection, 2020 - Elsevier
Antimicrobial resistance (AMR) represents a major challenge to global health. This problem
is most apparent in healthcare facilities, with a comparatively small number of pathogens …

The tRNA methyltransferase TrmB is critical for Acinetobacter baumannii stress responses and pulmonary infection

JC McGuffey, CD Jackson-Litteken, G Di Venanzio… - Mbio, 2023 - Am Soc Microbiol
Successful pathogens must be able to adapt to a multitude of stressors imposed by their
host. Acinetobacter baumannii has emerged as a major global health threat due to its …

Lipocalin-2 is an essential component of the innate immune response to Acinetobacter baumannii infection

JR Sheldon, LE Himmel, DE Kunkle, AJ Monteith… - PLoS …, 2022 - journals.plos.org
Acinetobacter baumannii is an opportunistic pathogen and an emerging global health threat.
Within healthcare settings, major presentations of A. baumannii include bloodstream …

Modulating isoprenoid biosynthesis increases lipooligosaccharides and restores Acinetobacter baumannii resistance to host and antibiotic stress

LD Palmer, KE Minor, JA Mettlach, ES Rivera, KL Boyd… - Cell reports, 2020 - cell.com
Acinetobacter baumannii is a leading cause of ventilator-associated pneumonia and a
critical threat due to multidrug resistance. The A. baumannii outer membrane is an …

Synergistic therapeutic efficacy of ebselen and silver ions against multidrug-resistant Acinetobacter baumannii-induced urinary tract infections

C Dong, J Wang, H Chen, P Wang, J Zhou, Y Zhao… - Metallomics, 2020 - academic.oup.com
Abstract Ebselen (EbSe), an organo-selenium compound with well-characterized toxicology
and pharmacology, exhibited potent antibacterial activity against glutathione (GSH)-positive …

Aerosolized delivery of ESKAPE pathogens for murine pneumonia models

K Rox, E Medina - Scientific Reports, 2024 - nature.com
Murine pneumonia models for ESKAPE pathogens serve to evaluate novel antibacterials or
to investigate immunological responses. The majority of published models uses intranasal …

Hyaluronic acid and antimicrobial peptide-modified gold/silver hybrid nanocages to combat bacterial multidrug resistance

J Yang, Y Zhao, J Cao, C Gong, J Zuo, N Zhang… - International Journal of …, 2020 - Elsevier
Bacterial multidrug resistance is a major challenge for the treatment of infection. In this study,
a gold-silver hybrid nanocage (Au/Ag NCs) is designed to conjugated with an antimicrobial …