The Physiology of Enteric Glia

J Gonzales, BD Gulbransen - Annual Review of Physiology, 2024 - annualreviews.org
Enteric glia are the partners of neurons in the enteric nervous system throughout the
gastrointestinal tract. Roles fulfilled by enteric glia are diverse and contribute to maintaining …

Mini-review: Intercellular communication between enteric glia and neurons

B Thomasi, B Gulbransen - Neuroscience letters, 2023 - Elsevier
The enteric nervous system is a dense network of enteric neurons and glia housed in the
gastrointestinal tract. This system is responsible for performing several functions that enable …

IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer

L van Baarle, V De Simone, L Schneider… - Nature …, 2024 - nature.com
Enteric glia have been recently recognized as key components of the colonic tumor
microenvironment indicating their potential role in colorectal cancer pathogenesis. Although …

Gingerenone A Attenuates Ulcerative Colitis via Targeting IL‐17RA to Inhibit Inflammation and Restore Intestinal Barrier Function

J Liang, W Dai, C Liu, Y Wen, C Chen, Y Xu… - Advanced …, 2024 - Wiley Online Library
Ulcerative colitis (UC) is a complicated and recurrent intestinal disease. Currently available
drugs for UC treatment are scarce, therefore, novel therapeutic drugs for the UC are urgently …

Guardians of the gut: influence of the enteric nervous system on the intestinal epithelial barrier

M Bubeck, C Becker, JV Patankar - Frontiers in Medicine, 2023 - frontiersin.org
The intestinal mucosal surface forms one of the largest areas of the body, which is in direct
contact with the environment. Co-ordinated sensory functions of immune, epithelial, and …

Enteric Glia

M Rao, BD Gulbransen - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
Enteric glia are a unique type of peripheral neuroglia that accompany neurons in the enteric
nervous system (ENS) of the digestive tract. The ENS displays integrative neural circuits that …

Enteric glia at center stage of inflammatory bowel disease

C Le Berre, P Naveilhan, M Rolli-Derkinderen - Neuroscience Letters, 2023 - Elsevier
Although our understanding of the pathophysiology of inflammatory bowel disease (IBD) is
increasing, the expanding body of knowledge does not simplify the equation but rather …

Functional analysis of antigen presentation by enteric glial cells during intestinal inflammation

RM Brown, HH Le, IW Babcock, TH Harris, A Gaultier - Glia, 2024 - Wiley Online Library
Abstract The Enteric Nervous System is composed of a vastly interconnected network of
neurons and glial cells that coordinate to regulate homeostatic gut function including …

Enteric neuro-immune interactions in intestinal health and disease

L van Baarle, M Stakenborg, G Matteoli - Seminars in Immunology, 2023 - Elsevier
The enteric nervous system is an autonomous neuronal circuit that regulates many
processes far beyond the peristalsis in the gastro-intestinal tract. This circuit, consisting of …

Enteric glia as a player of gut-brain interactions during Parkinson's disease

B Thomasi, L Valdetaro, MC Ricciardi… - Frontiers in …, 2023 - frontiersin.org
The enteric glia has been shown as a potential component of neuroimmune interactions that
signal in the gut-brain axis during Parkinson's disease (PD). Enteric glia are a peripheral …