[HTML][HTML] Advances in single-cell RNA sequencing and its applications in cancer research

D Huang, N Ma, X Li, Y Gou, Y Duan, B Liu… - Journal of hematology & …, 2023 - Springer
Cancers are a group of heterogeneous diseases characterized by the acquisition of
functional capabilities during the transition from a normal to a neoplastic state. Powerful …

Diffuse large B-cell lymphoma

M Martelli, AJM Ferreri, C Agostinelli, A Di Rocco… - Critical reviews in …, 2013 - Elsevier
Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoid malignancy in adults
accounting for 31% of all NHL in Western Countries. Following, morphological, biological …

The international consensus classification of mature lymphoid neoplasms: a report from the clinical advisory committee

E Campo, ES Jaffe, JR Cook… - Blood, The Journal …, 2022 - ashpublications.org
Since the publication of the Revised European-American Classification of Lymphoid
Neoplasms in 1994, subsequent updates of the classification of lymphoid neoplasms have …

[PDF][PDF] Effect of ibrutinib with R-CHOP chemotherapy in genetic subtypes of DLBCL

WH Wilson, GW Wright, B Hodkinson… - Cancer cell, 2021 - cell.com
In diffuse large B cell lymphoma (DLBCL), tumors belonging to the ABC but not GCB gene
expression subgroup rely upon chronic active B cell receptor signaling for viability, a …

ROBUST: a phase III study of lenalidomide plus R-CHOP versus placebo plus R-CHOP in previously untreated patients with ABC-type diffuse large B-cell lymphoma

GS Nowakowski, A Chiappella… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Patients with the activated B-cell-like (ABC) subtype of diffuse large B-cell
lymphoma (DLBCL) historically showed inferior survival with standard rituximab plus …

Targeted sequencing in DLBCL, molecular subtypes, and outcomes: a Haematological Malignancy Research Network report

SE Lacy, SL Barrans, PA Beer, D Painter… - Blood, The Journal …, 2020 - ashpublications.org
Based on the profile of genetic alterations occurring in tumor samples from selected diffuse
large B-cell lymphoma (DLBCL) patients, 2 recent whole-exome sequencing studies …

[PDF][PDF] Genetic and functional drivers of diffuse large B cell lymphoma

A Reddy, J Zhang, NS Davis, AB Moffitt, CL Love… - Cell, 2017 - cell.com
Diffuse large B cell lymphoma (DLBCL) is the most common form of blood cancer and is
characterized by a striking degree of genetic and clinical heterogeneity. This heterogeneity …

Clinical and biological subtypes of B-cell lymphoma revealed by microenvironmental signatures

N Kotlov, A Bagaev, MV Revuelta, JM Phillip… - Cancer discovery, 2021 - AACR
Diffuse large B-cell lymphoma (DLBCL) is a biologically and clinically heterogeneous
disease. Transcriptomic and genetic characterization of DLBCL has increased the …

A multiprotein supercomplex controlling oncogenic signalling in lymphoma

JD Phelan, RM Young, DE Webster, S Roulland… - Nature, 2018 - nature.com
B cell receptor (BCR) signalling has emerged as a therapeutic target in B cell lymphomas,
but inhibiting this pathway in diffuse large B cell lymphoma (DLBCL) has benefited only a …

[HTML][HTML] Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype

SC Oh, BH Sohn, JH Cheong, SB Kim, JE Lee… - Nature …, 2018 - nature.com
Gastric cancer is a heterogeneous cancer, making treatment responses difficult to predict.
Here we show that we identify two distinct molecular subtypes, mesenchymal phenotype …