Positron emission tomography (PET) is an important driver for present day healthcare.
Fluorine-18 is the most widely used radioisotope for PET imaging and a thorough overview …

This review highlights the progress of aqueous fluoroalkylation over the past few decades.
Fluorine-containing functionalities are important design elements in new pharmaceuticals …

All fluorochemicals—including elemental fluorine and nucleophilic, electrophilic, and radical
fluorinating reagents—are prepared from hydrogen fluoride (HF). This highly toxic and …

Cross-coupling chemistry is widely applied to carbon-carbon bond formation in the synthesis
of medicines, agrochemicals, and other functional materials. Recently, single-electron …

The introduction of a monofluoromethyl moiety has undoubtedly become a very important
area of research in recent years. Owing to the beneficial properties of organofluorine …

This communication describes a mild, amide-directed fluorination of benzylic, allylic, and
unactivated C–H bonds mediated by iron. Upon exposure to a catalytic amount of iron (II) …

A process for the direct hydrofluoromethylation of alkenes is reported for the first time. This
straighforward silyl radical-mediated reaction utilises CH2FI as a non-ozone depleting …

The new millennium has witnessed the rapid development of synthetic organofluorine
chemistry all over the world, and chemists in China have made significant contributions in …

The first direct and straightforward nucleophilic fluoromethylation of organic compounds is
reported. The tactic employs a “fleeting” lithium fluorocarbenoid (LiCH2F) generated from …

The first example of nickel‐catalyzed decarboxylative fluoroalkylation of α, β‐unsaturated
carboxylic acids has been developed with commonly available fluoroalkyl halides. This …