Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

APT‐weighted MRI: techniques, current neuro applications, and challenging issues

J Zhou, HY Heo, L Knutsson… - Journal of Magnetic …, 2019 - Wiley Online Library
Amide proton transfer‐weighted (APTw) imaging is a molecular MRI technique that
generates image contrast based predominantly on the amide protons in mobile cellular …

[HTML][HTML] Paramagnetic NMR in solution and the solid state

AJ Pell, G Pintacuda, CP Grey - Progress in nuclear magnetic resonance …, 2019 - Elsevier
The field of paramagnetic NMR has expanded considerably in recent years. This review
addresses both the theoretical description of paramagnetic NMR, and the way in which it is …

Magnetization transfer contrast and chemical exchange saturation transfer MRI. Features and analysis of the field-dependent saturation spectrum

PCM Van Zijl, WW Lam, J Xu, L Knutsson, GJ Stanisz - Neuroimage, 2018 - Elsevier
Abstract Magnetization Transfer Contrast (MTC) and Chemical Exchange Saturation
Transfer (CEST) experiments measure the transfer of magnetization from molecular protons …

Chemical exchange saturation transfer (CEST): what is in a name and what isn't?

PCM Van Zijl, NN Yadav - Magnetic resonance in medicine, 2011 - Wiley Online Library
Chemical exchange saturation transfer (CEST) imaging is a relatively new magnetic
resonance imaging contrast approach in which exogenous or endogenous compounds …

Clinical applications of chemical exchange saturation transfer (CEST) MRI

KM Jones, AC Pollard, MD Pagel - Journal of Magnetic …, 2018 - Wiley Online Library
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has
been developed and employed in multiple clinical imaging research centers worldwide …

Magnetic resonance imaging of glutamate

K Cai, M Haris, A Singh, F Kogan, JH Greenberg… - Nature medicine, 2012 - nature.com
Glutamate, a major neurotransmitter in the brain, shows a pH-and concentration-dependent
chemical exchange saturation transfer effect (GluCEST) between its amine group and bulk …

Challenges for molecular magnetic resonance imaging

E Terreno, DD Castelli, A Viale, S Aime - Chemical reviews, 2010 - ACS Publications
Challenges for Molecular Magnetic Resonance Imaging | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most …

Studying “invisible” excited protein states in slow exchange with a major state conformation

P Vallurupalli, G Bouvignies, LE Kay - Journal of the American …, 2012 - ACS Publications
Ever since its initial development, solution NMR spectroscopy has been used as a tool to
study conformational exchange. Although many systems are amenable to relaxation …

Water saturation shift referencing (WASSR) for chemical exchange saturation transfer (CEST) experiments

M Kim, J Gillen, BA Landman, J Zhou… - … in Medicine: An …, 2009 - Wiley Online Library
Chemical exchange saturation transfer (CEST) is a contrast mechanism that exploits
exchange‐based magnetization transfer (MT) between solute and water protons. CEST …