Vascular endothelial growth factors (VEGFs), initially thought to act specifically on the
vascular system, exert trophic effects on neural cells during development and adulthood …

Insulin and insulin-like growth factor 1 (IGF1) signalling play a central role in the
development and maintenance of neurons in the brain, and in humans neurodevelopmental …

Alzheimer's disease (AD) is a progressive neurodegenerative disease with memory loss and
cognitive decline. Neurofibrillary tangles (NFTs) formed by hyperphosphorylated Tau protein …

IgLON proteins are GPI anchored adhesion molecules that control neurite outgrowth. In
particular, Negr1 down-regulation negatively influences neuronal arborization in vitro and in …

Spinal Muscular Atrophy (SMA) is a neuromuscular disorder caused by mutations in the
SMN1 gene. Being a monogenic disease, it is characterized by high clinical heterogeneity …

The herb Centella asiatica has long been considered a memory tonic. A recent review found
no strong evidence for improvement of cognitive function, suggesting negative results were …

Growth factors such as nerve growth factor and glial cell line-derived neurotrophic factor are
known to induce pain sensitization. However, a plethora of other growth factors is released …

The monogenetic disease Spinal Muscular Atrophy (SMA) is characterized by a progressive
loss of motoneurons leading to muscle weakness and atrophy due to severe reduction of the …

Intracellular signal transduction in response to growth factor receptor activation is a
fundamental process during the regeneration of the nervous system. In this context …

The findings of a recent study associate LPHN3, a member of the latrophilin family, with an
increased risk of developing attention deficit/hyperactivity disorder (ADHD), the most …