Using clusterProfiler to characterize multiomics data
With the advent of multiomics, software capable of multidimensional enrichment analysis
has become increasingly crucial for uncovering gene set variations in biological processes …
has become increasingly crucial for uncovering gene set variations in biological processes …
Analysis of microbial compositions: a review of normalization and differential abundance analysis
H Lin, SD Peddada - NPJ biofilms and microbiomes, 2020 - nature.com
Increasingly, researchers are discovering associations between microbiome and a wide
range of human diseases such as obesity, inflammatory bowel diseases, HIV, and so on …
range of human diseases such as obesity, inflammatory bowel diseases, HIV, and so on …
Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients
EN Baruch, I Youngster, G Ben-Betzalel, R Ortenberg… - Science, 2021 - science.org
The gut microbiome has been shown to influence the response of tumors to anti–PD-1
(programmed cell death–1) immunotherapy in preclinical mouse models and observational …
(programmed cell death–1) immunotherapy in preclinical mouse models and observational …
A new genomic blueprint of the human gut microbiota
The composition of the human gut microbiota is linked to health and disease, but knowledge
of individual microbial species is needed to decipher their biological roles. Despite …
of individual microbial species is needed to decipher their biological roles. Despite …
[HTML][HTML] A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock… - Cell, 2022 - cell.com
Treatment of severe COVID-19 is currently limited by clinical heterogeneity and incomplete
description of specific immune biomarkers. We present here a comprehensive multi-omic …
description of specific immune biomarkers. We present here a comprehensive multi-omic …
Caloric restriction disrupts the microbiota and colonization resistance
Diet is a major factor that shapes the gut microbiome, but the consequences of diet-induced
changes in the microbiome for host pathophysiology remain poorly understood. We …
changes in the microbiome for host pathophysiology remain poorly understood. We …
Microbiome datasets are compositional: and this is not optional
Datasets collected by high-throughput sequencing (HTS) of 16S rRNA gene amplimers,
metagenomes or metatranscriptomes are commonplace and being used to study human …
metagenomes or metatranscriptomes are commonplace and being used to study human …
From hairballs to hypotheses–biological insights from microbial networks
L Röttjers, K Faust - FEMS microbiology reviews, 2018 - academic.oup.com
Microbial networks are an increasingly popular tool to investigate microbial community
structure, as they integrate multiple types of information and may represent systems-level …
structure, as they integrate multiple types of information and may represent systems-level …
Allogenic fecal microbiota transplantation in patients with nonalcoholic fatty liver disease improves abnormal small intestinal permeability: a randomized control trial
L Craven, A Rahman, SN Parvathy… - Official journal of the …, 2020 - journals.lww.com
METHODS: Twenty-one patients with NAFLD were recruited and randomized in a ratio of 3:
1 to either an allogenic (n= 15) or an autologous (n= 6) FMT delivered by using an …
1 to either an allogenic (n= 15) or an autologous (n= 6) FMT delivered by using an …
ggpicrust2: an R package for PICRUSt2 predicted functional profile analysis and visualization
Microbiome research is now moving beyond the compositional analysis of microbial taxa in
a sample. Increasing evidence from large human microbiome studies suggests that …
a sample. Increasing evidence from large human microbiome studies suggests that …