Simple Summary Radiotherapy with carbon ions has been used for over 20 years in Asia
and Europe and is now planned in the USA. The physics advantages of carbon ions …

The treatment of cancer with proton radiation therapy was first suggested in 1946 followed
by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated …

Helium ion beam therapy for the treatment of cancer was one of several developed and
studied particle treatments in the 1950s, leading to clinical trials beginning in 1975 at the …

Clinical treatment with protons uses the concept of relative biological effectiveness (RBE) to
convert the absorbed dose into an RBE-weighted dose that equals the dose for radiotherapy …

Radiation therapy plays an important role in the multidisciplinary management of breast
cancer. Recent years have seen improvements in breast cancer survival and a greater …

In this review article, we review the 3 important aspects of linear-energy-transfer (LET) in
intensity-modulated proton therapy (IMPT) for head and neck (H&N) cancer management …

Recently, a number of clinical studies have explored links between possible Relative
Biological Effectiveness (RBE) elevations and patient toxicities and/or image changes …

Purpose To develop and validate combined ion-beam with constant relative biological
effectiveness (RBE)(CICR) particle therapy in single field arrangements for improved …

Simple Summary The increasing global demand and accessibility for proton beam therapy
has been fueled by its recognised clinical benefits over traditional radiotherapy, primarily its …

Purpose Present-day treatment planning in carbon ion therapy is conducted with
assumptions for a limited number of tissue types and models for effective dose. Here, we …