The greatest challenge associated with topical drug delivery for the treatment of diseases
affecting the posterior segment of the eye is to overcome the poor bioavailability of the …

Recent high-profile failures of Alzheimer disease treatments at the clinical trial stage have
led to renewed efforts to identify and test novel interventions for Alzheimer disease and …

Background Visual impairment and interventions to preserve vision may impact dementia
risk. Thus, we aimed to explore the associations of cataract and cataract surgery with the risk …

Associations between sensory status and cognitive performance are now widely reported.
However, important open questions remain, including whether the associations are similar …

Introduction: Cognitive frailty is associated with higher risk of dementia and adverse health
outcomes. However, multidimensional factors that influence cognitive frailty transitions are …

PURPOSE To evaluate the association between vision impairment (VI) and cognitive
function using objective measures. DESIGN Cross-sectional analysis with a nationally …

Background Age-related eye diseases and cognitive frailty (CF) are both important
predictors of adverse health outcomes in older adults, however, little is known about their …

Background To evaluate whether contrast sensitivity is associated with lower extremity
physical function in cognitively intact older adults. Methods Cross-sectional analysis of the …

Objectives: We investigated factors associated with job retention after developing a visual
impairment in late middle adulthood. Methods: Using longitudinal survey data from the …

The survey found that many interactive interfaces of apps developed for the elderly on the
market do not align with the visual characteristics of the elderly in terms of color …